Society of Cardiology have established benchmarks for patient transfer times (door-indoor out time and door-to-balloon time) that serve as clinical performance measures for ST-segment–elevation myocardial infarction (STEMI) networks. Campaigns, such as D2B Alliance and Mission Lifeline, were also launched in an effort to reduce system delays in transfer and improve outcomes for subjects present...

T hrombolysis as a treatment for ischemic stroke is only indicated within the first 3 to 4.5 hours after onset of symptoms, and is more efficacious the earlier it is given. Patients must thus seek help, receive a clinical diagnosis, and reach a center of care for imaging and treatment without delay. This is a problem in remote and rural areas, leading to a relative disadvantage for rural dwelle...

Background: Motor function impairment occurs in approximately two-thirds of patients with subcortical stroke. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique for modulating cortical excitability. Objectives: The present study was designed for assessing the efficacy of high-frequency rTMS (5 Hz) on ipsilesional primary motor cortex in patients with subcortical stro...

Background and Purpose—Systemic thrombolysis represents the only proven therapy for acute ischemic stroke, but safe treatment is reported only in established stroke units. One major goal of the ongoing Telemedic Pilot Project for Integrative Stroke Care (TEMPiS) in Bavaria is to extend the use of tissue plasminogen activator (tPA) treatment in nonurban areas through telemedic support. Methods—T...

Background and purposeUncomfortable care histamine H2 antagonist (H2A) are implicated in precipitating delirium. In acute stroke, however, the need for them depends on stroke severity, an established risk factor So, it is unclear whether or H2A itself responsible We aimed to evaluate their causal effects delirium patients.MethodsThis a prospective cohort study patients admitted unit. Patients w...

In the present work, we reported a new nuclear Overhauser enhancement (NOE)-mediated magnetization transfer (MT) signal at around -1.6ppm (NOE(-1.6)) in rat brain and investigated its application in the detection of acute ischemic stroke in rodent model. Using continuous wave (CW) MT sequence, the NOE(-1.6) is reliably detected in rat brain. The amplitude of this new NOE signal in rat brain was...

ore than a thousand years ago on a battlefield in ancient Palestine, a shepherd boy (David) defeated a mighty fully armored warrior (Goliath) with a stone and a sling. Comprehensive Stroke Centers (CSC), the Goliath of stroke care, are typically high-volume, more experienced, and more resourced compared with conventional Stroke Units (SU) at community hospitals—David's. 1 Although the benefits ...

A set of algorithms is proposed in this paper to automatically transform 3D animal models to Chinese painting style. Inspired by real painting process in Chinese painting of animals, we divide the whole rendering process into two parts: borderline stroke making and interior shading. In borderline stroke making process we first find 3D model silhouettes in real-time depending on the viewing dire...

Many MRI parameters have been explored and demonstrated the capability or potential to evaluate acute stroke injury, providing anatomical, microstructural, functional, or neurochemical information for diagnostic purposes and therapeutic development. However, the application of multiparameter MRI approach is hindered in clinic due to the very limited time window after stroke insult. Parallel ima...

In January 2007, a telestroke system was established between a community hospital lacking a neurologist on call and a stroke centre 70 km away. The telestroke system allowed urgent remote evaluation of the patient by a specialized neurologist, supervised thrombolytic treatment or a decision for urgent transfer to the stroke centre. During the first year of operation of the telestroke system, we...