The use of light-driven imaging techniques for the diagnosis of breast cancer dates back to as early as 1929. Transillumination was evaluated for potential differentiation of breast lesions, e.g. to distinguish benign cysts from solid tumours. Cutler summed the technique to be “...a simple procedure and a valuable aid in the interpretation of pathological conditions in the mammary gland. Its us...

CASE REPORT A 61-year-old pseudophakic male with recurrent blurred vision episodes associated with uveitis, hyphema, glaucoma and vitreous hemorrhage. Iris transillumination defects and apposition of the optic and iris were found. The patient was diagnosed with Uveitis-Glaucoma-Hyphema (UGH) Syndrome. DISCUSSION Mechanical irritation of the iris is a consequence of intraocular lens malpositio...

We have developed a methodology that can be used in reconstruction algorithms to quantify the optical coefficients and the geometrical cross section of a weakly abnormal optical target embedded in an otherwise homogeneous medium. This novel procedure uses differenttime-dependent point-spread functions to analyze the diffusive and absorptive contrasts obtained from time-of-flight measurements. D...

We investigated the contributions of Tyrp1 and Gpnmb to the iris transillumination defect (TID) in five age cohorts of BXD mice. Using systems genetics, we also evaluated the role of other known pigmentation genes (PGs). Mapping studies indicate that Tyrp1 contributes to the phenotype at all ages, yet the TID maps to Gpnmb only in the oldest cohort. Composite interval mapping reveals secondary ...

AIM To examine the relation of overventilation and other clinical events to the development of pneumothoraces in ventilated neonates. METHODS A case-control study. RESULTS Fifty three (8.7%) of 606 ventilated neonates developed a pneumothorax. Eighteen (34%) cases and 23 (43%) controls were unintentionally overventilated (PaCO(2) < 4 kPa) at some time before the pneumothorax developed in th...

INTRODUCTION The annual examination of first graders' oral health as stipulated by law aimed to reach every child in Rhineland-Palatinate (Germany) in their first year of school. We intended to evaluate the first graders' oral health based on the examination data for 2013/2014. METHODS Instructed examiners measured the d3mft(deciduous)/D3MFT(permanent) index according to World Health Organiza...