Dogs given nonmyeloablative conditioning and marrow grafts from 2 dog leukocyte antigen (DLA)-identical littermate donors developed stable trichimerism and stably accepted a subsequent kidney graft from one of the marrow donors without the need for immunosuppression. In this study, we used trichimeras to evaluate strategies for adoptive immunotherapy to solid tumors, using the kidney as a tumor...

Most transplanted kidneys are from cadavers, but there are also substantial numbers of transplants from live donors. Recently, there have started to be kidney exchanges involving two donor-patient pairs such that each donor cannot give a kidney to the intended recipient because of immunological incompatibility, but each patient can receive a kidney from the other donor. Exchanges are also made ...

INTRODUCTION Despite increased utilization of marginal organs, there is still a marked disparity between organ supply and demand for transplantation. To maximize resources, it is imperative that procured organs are in good condition. Surgical damage at organ recovery can happen and organs are sometimes discarded as a result. We describe a damaged recovered kidney with high ureteric transection ...

Organ transplantation is the procedure of replacing diseased organs, parts of organs, or tissues by healthy organs or tissues. The transplanted organ or tissue can be obtained either from the patient himself (= autograft), from another human donor (= allograft) or from an animal (= xenograft). Transplanted organs may be artificial or natural, whole (such as kidney, heart and liver) or partial (...

background: the purpose of this study was to characterize the pharmacokinetic parameters of mycophenolic acid (mpa) in iranian kidney transplant patients. methods: plasma mpa concentration of mycophenolate mofetile (mmf) 1 gram two times a day was measured in 21 iranian kidney transplant recipients receiving treatment. patients who entered the study had been transplanted for more than 3 months ...