Purpose To evaluate the clinical classification and characteristics of hereditary optic neuropathy patients in a single center in China. Method Retrospective case study. Patients diagnosed with hereditary optic neuropathy between January 2014 and December 2015 in the neuro-ophthalmology division in Shanghai Eye and ENT Hospital of Fudan University were recruited. Clinical features as well as ...

OBJECTIVE To identify and follow a series of 52 patients with optic neuropathy related to sarcoidosis. METHODS Prospective observational cohort study. RESULTS The disorder was more common in women and affected a wide age range. It was proportionately more common in African and Caribbean ethnic groups. Two clinical subtypes were identified: the more common was a subacute optic neuropathy res...

BACKGROUND To report a case of bilateral optic disc oedema and associated optic neuropathy in the setting of FOLFOX chemotherapy. CASE PRESENTATION A case of a 57-year-old male being treated with FOLFOX chemotherapy for stage 3B colorectal cancer, who developed bilateral optic disc oedema and associated left sided optic neuropathy is described. The patient presented following cycles 7, 8 and ...

PURPOSE The purpose of this study is to identify risk factors for severe thyroid-associated orbitopathy (TAO) and compressive optic neuropathy in Korean patients. METHODS This study was a retrospective comparative case series. All TAO patients who were first seen at our institution between 2005 and 2009 and who had follow-up periods of at least 6 months were included. Patients were divided in...

purpose: to report a case of enophthalmos secondary to complete globe dislocation into the maxillary sinus due to orbital fracture. patient and findings: an 18-year-old man was referred to labafinejad hospital, one week after a car accident. at initial examination, the globe was not seen within the right orbit. a large floor fracture and globe luxation into the right maxillary sinus were confir...

BACKGROUND AND PURPOSE MR imaging characteristics of optic neuropathy caused by cat scratch disease have not yet been described; this lack of information may result in incorrect diagnosis and may contribute to initiation of inappropriate therapy. Our study was based on the hypothesis that cat scratch disease-related optic neuropathy has distinct MR imaging features compared with those of other ...

Inherited disorders of the optic nerve significantly impact vision in children and adults. The optic nerve disorders most commonly encountered clinically are glaucoma and primary optic neuropathy including Leber's hereditary optic neuropathy (LHON) and autosomal dominant or Kjer's optic atrophy. Current knowledge of the genetics of optic neuropathy and glaucoma makes it possible to test for mut...

BACKGROUND Optic neuropathy is a rare manifestation of systemic lupus erythematosus (SLE). In a previous series most patients with optic neuropathy in association with SLE had a final visual acuity of 20/200 or less despite corticosteroid therapy. METHODS Three patients (five affected eyes) with severe retrobulbar optic neuropathy in association with SLE were treated promptly with intravenous...

Leber's Hereditary Optic Neuropathy is a rare disease caused by mutation in the mitochondrial DNA. It appears most often young men, leading to profound, permanent loss of vision short time. There no specific treatment for this condition.Idebenone medicine that administered patients with hereditary optic neuropathy improves or stops deterioration vision. Increasing number people during therapy a...