Diabetic rats in long-term display an augmented nociceptive response to chemical, mechanical, and thermal stimuli. Furthermore, hyperalgesia is one of the major symptoms of diabetic neuropathy in some patients. Considering the antidiabetic potential of chard, this study was carried out to evaluate the possible analgesic effect of chard-mixed food intake in male streptozotocin-induced diabetic r...

background and aims. statins, the mevalonate pathway inhibitors, have effects on bone formation in vitro and in vivo. the aim of the present study was to investigate whether injection of statins could lead to ectopic bone formation in rats. materials and methods. a single dose (0.5 mg) of simvastatin, atrovastatin, lovastatin and polyethylene glycol (control material) were injected into four qu...

Well-Structured Transitions Systems (WSTS) constitute a generic class of infinite-state systems for which several properties like coverability remain decidable. The family of coverability languages that they generate is an appropriate criterium for measuring their expressiveness. Here we establish that Petri Data nets (PDNs) and Timed Petri nets (TdPNs), two powerful classes of WSTS are equival...

Aim: There are Conflicting reports on safety profile of nanoparticles biological cells. This study evaluated the impact nanosilver hemocompatibility salt-loaded rats. Materials and Methods: Sprague-Dawley rats [(inbred) (120-140 g)] randomly divided into 4 groups, (n = 6) were studied. Group 1(control) received normal rat chow tap water, 2 containing 8% NaCl [(salt-loaded (SLRs)]. 3 + Nanosilve...

Background: This study was undertaken to investigate whether treatment with vitamin E and N acetyl cystein protects rat sperm by inhibiting reactive oxygen species generation induced by lead (Pb) exposure. Materials and Methods: After an acclimatization period of one week, 20 Male rats were divided into 4 groups of 5 rats each. Animals within different treatment groups were maintained on their ...

1. The activities of gluconeogenic and glycolytic enzymes and the concentrations of citrate, ammonia, amino acids, glycogen, glucose 6-phosphate, acetyl-CoA, lactate and pyruvate were measured in kidney cortex of normal, diabetic, cortisone-treated and growth hormone-treated rats. 2. In kidney cortex of diabetic, cortisone-treated and growth hormone-treated rats the activities of glucose 6-phos...

Acute morphine withdrawal is considered to be the physical manifestation of dependence, emerging when morphine administration is stopped or after the administration of an opiate antagonist, such as naloxone. Gabapentin, which is an antiepileptic, agent, enhances the analgesic effect of morphine in healthy volunteers, but its effect on morphine dependence and withdrawal signs has not determined ...