Starting from the most general formulation of stochastic thermodynamics—i.e. a thermodynamically consistent nonautonomous stochastic dynamics describing systems in contact with several reservoirs—, we de€ne a procedure to identify the conservative and the minimal set of nonconservative contributions in the entropy production. Œe former is expressed as the di‚erence between changes caused by tim...

A simulation of gene expression plays a central role in the simulation of cells or \systems biology". Recently, reporter protein technique has revealed the randomness in gene expression [2]. The experiments of uorescent reporter proteins suggests a high volatility of gene transcriptions. On the other hand, a phenomena of sporadic gene transcription has been observed by in situ hybridization tec...

In this paper we describe the design and implementation of a system called the Network Weather Service (NWS) that takes periodic measurements of deliverable resource performance from distributed networked resources, and uses numerical models to dynamically generate forecasts of future performance levels. These performance forecasts, along with measures of performance uctuation (e.g. the mean sq...

Neonatal Bacille Calmette Guérin (BCG) vaccination has been reported to have beneficial effects beyond preventing infantile tuberculous meningitis and miliary disease. We hypothesized that BCG vaccine given at birth would enhance T-helper 1 (Th1) immune responses to the first vaccines given later in infancy. We conducted a nested case-control study of neonatal BCG vaccination and its heterologo...

This study investigates the impact of item parameter drift (IPD) on parameter and ability estimation when the underlying measurement model fits a mixture distribution, thereby violating the item invariance property of unidimensional item response theory (IRT) models. An empirical study was conducted to demonstrate the occurrence of both IPD and an underlying mixture distribution using real-worl...

Objective. To dissect the characteristics of adrenal medullary hyperplasia (AMH) and share our experience of diagnosis and treatment of AMH. Methods. From 1999 to 2013, 12 cases of AMH have been pathologically diagnosed after operation in our hospital. The clinical characteristics, process of diagnosis, treatment, and prognosis during follow-up of all patients are summarized retrospectively. Re...

Channel Archiver is a generic periodic sampling toolset for EPICS. Using the EPICS Channel Access (CA) network protocol, it can collect real-time data from any CA server on the network. Ion Cyclotron Resonance Heating (ICRH) Data Acquisition and Control (DAC) system uses the Experimental Physics and Industrial Control System (EPICS) and MDSplus software packages. In, two fundamentally different...

Past research on dynamic workplace performance evaluation has taken as axiomatic that temporal performance trends produce naïve extrapolation effects on performance ratings. That is, we naïvely assume that an individual whose performance has trended upward over time will continue to improve, and rate that individual more positively than an individual whose performance has trended downward over ...

In highly adaptive irregular problems such as many Particle-In-Cell (PIC) codes and Direct Simulation Monte Carlo (DSMC) codes, data access patterns may vary from time step to time step. This uctuation may hinder eecient utilization of distributed memory parallel computers because of the resulting overhead for data redistribution and dynamic load balancing. To eeciently parallelize such adap-ti...

The reaction{diiusion process corresponding to the Fisher{Kolmogorov equation is studied by means of a discrete multivariate master equation. For travelling wave fronts the stability criterion necessary for the applicability of a system{size expansion is shown to be violated due to the existence of a zero mode of the rst variational equation. This zero mode is connected to the translational inv...