PURPOSE To examine the effect of sodium copper chlorophyllin complex on the expression of biomarkers of photoaged dermal extracellular matrix indicative of skin repair. PATIENTS AND METHODS Following a previously published 12-day clinical assessment model, skin biopsy samples from the forearms of four healthy females with signs of photoaged skin were obtained and samples were analyzed by immu...

Maintenance of proper moisture and regulation of infection are simultaneously required to promote healing of pressure ulcers. Continuous use of water-rich ointment may often lead to excess moisture and induce edematous granulation tissue. Use of water soluble ointment may excessively absorb exudates and induce dry granulation tissue. Selection of appropriate topical ointment is desired to avoid...

INTRODUCTION Oral leukoplakia (OL) is the most common potentially malignant lesion of the oral cavity. AIM The purpose of the study was clinical and epidemiological analysis of patients with OL diagnosed and treated in the Department of Maxillofacial and Oral Surgery, Medical University of Gdansk, comparison of effectiveness of treatment methods, defining whether van der Waal level of OL infl...

Dr. Antonio Ledo, Castellana 167, E-28046, Madrid (Spain) Syringoma is a common benign tumor of eccrine sweat gland origin which usually appears around the eyelids. Eruptive syringoma is a rare variant of syringoma that appears in successive crops on anterior surfaces of the trunk, neck and arms. We present a patient with eruptive syringoma who showed a satisfactory response to therapy with top...

Retinoic acid and transforming growth factor(TGF) affect differentiation, proliferation and carcinogenesis of epithelial cells. The effect of both compounds on the proliferation of cells of the hormone sensitive human breast cancer cell line (ER+) MCF-7 was assessed in the presence of estradiol and tamoxifen. The assay was based on [H]thymidine incorporation and the proliferative activity of PC...

Melasma is a common, acquired facial skin disorder, mostly involving sun-exposed areas like cheeks, forehead and upper lip. Melasma occurs in both sexes, although almost 90 percent of the affected are women. It is more common in darker skin types (Fitzpatrick skin types IV to VI) especially Hispanics/Latinos, Asians and African-Americans. The onset of the melasma is at puberty or later, with ex...

©2017 by Anais Brasileiros de Dermatologia Dear Editor, Tretinoin is a superficial peeling agent that has been used for a few years, with several clinical indications and low adverse effect levels.1 It is quite popular in Brazil due to its effectiveness, safety and low cost. There are few studies on tretinoin peeling in the literature.2 The ideal concentration is still undefined, therefore the ...