The inhibitory effects of thapsigargin, cyclopiazonic acid, and 2,5-di(tert-butyl)hydroquinone, and 1,3-dibromo-2,4,6-tri(methylisothiouronium)benzene on the Ca(2+) ATPase were characterized by comparative measurements of sequential reactions of the catalytic and transport cycle, including biochemical measurements and detection of charge movements within a single cycle. In addition, patterns of...

In this paper, the energy absorption features of tri-layer explosive-welded deep-drawn cups subjected to quasi-static axial compressive loading are investigated numerically and experimentally. To produce the cups, tri-layer blanks composed of aluminum and stainless steel alloys were fabricated by an explosive-welding process and formed by a deep drawing setup. The quasi-static tests were carrie...

Schizosaccharomyces pombe Dim1p is required for maintaining the steady-state level of the anaphase-promoting complex or cyclosome (APC/C) component Lid1p and thus for maintaining the steady-state level and activity of the APC/C. To gain further insight into Dim1p function, we have investigated the mechanism whereby Dim1p influences Lid1p levels. We show that S. pombe cells lacking Dim1p or Sacc...

Treatment of carbon-yl(1,2-diphenylpenta-1,3-dien-1-yl-5-yl-idene)bis-(tri-phenyl-phosphane)iridium, [IrCO(-C(Ph)=C(Ph)-CH=CH-CH=)(PPh3)2], with either bromine or iodine produced di-bromido-(1,2-diphenylpenta-1,3-dien-1-yl-5-yl-idene)(tri-phenyl-phosphine)iridium(III), [IrBr2{-C(Ph)=C(Ph)-CH=CH-CH=}(PPh3)], (I), and (1,2-diphenylpenta-1,3-dien-1-yl-5-yl-idene)di-iodido-(tri-phenyl-phosphane)iri...

Following hybridization with embryonic stem (ES) cells, somatic genomes are epigenetically reprogrammed and acquire pluripotency. This results in the transcription of somatic genome-derived tissue-specific genes upon differentiation. During nuclear reprogramming, it is expected that DNA and chromatin modifications, believed to function in cell-type-specific epigenotype memory, should be signifi...

The aim of the present study was to investigate whether and by which mechanism; histamine can induce state-dependent retrieval of passive avoidance task. The pre-training or pre-test intracerebroventricular (i.c.v.) injection of histamine (20µg/mouse) impaired retrieval, when it was tested 24 h later. In the animals, which retrieval was impaired due to histamine pre-training administration, pre...

We show that pure states of multipartite quantum systems are multiseparable (i.e. give separable density matrices on tracing any party) if and only if they have a generalized Schmidt decomposition. Implications of this result for the quantification of multipartite pure-state entanglement are discussed. Further, as an application of the techniques used here, we show that any purification of a bi...

This paper proposed an ultra-low-power successive approximation register analog to digital converter (ADC) for medical implant devices. To reduce power consumption, the novel techniques presented in this are a tri-state capacitor unit, switch scheme, and new low static comparator. Tri-state unit reduces down without use of middle voltage reference. The scheme can complete most-significant bit 3...

Effect of different fillers on natural rubber compounds was investigated through curing, mechanical properties and morphology studies for improving mechanical performance of rubber articles. In this work, natural rubber blends with Silica as Single-filler compounds, and blends with Silica and Carbon black as Bi-filler compounds were considered. Then, natural rubber blends with Silica, Carbon bl...

irradiation of &methyl; spiro [2.5] oct-7-en-4-one through its singlet excited state resulted in the formation of 4-methyl spiro [2.5] oct-4-en -6-one. we have used the cyclopropyl moiety in the molecule as a probe to study the operating mechanism in the photochemistry of ?, ?-unsaturated compounds. the results showed that this photoisomerization probably occurs through a concerted process.