Introduction The parasite Trichomonas vaginalis is a haploid, flagellated, eukaryotic microbe that adheres to the human urogenital tract and causes the most common sexually transmitted parasitic infection, trichomoniasis ("trich"), with around 250 million new cases reported annually worldwide and about 7 million cases in the United States [1]. Previously considered a female “nuisance disease,” ...

BACKGROUND/PURPOSE(S) Trichomoniasis caused by Trichomonas vaginalis is the most common non-viral sexually transmitted infection. Morphological transformation from the trophozoite stage to the amoeboid or pseudocyst stage is crucial for T. vaginalis infection and survival. Protein phosphorylation is a key post-translational modification involved in the regulation of several biological processes...

Number 20 Last year I wrote a two-part essay on herpes simplex virus infections. 1z In it, I noted that although herpes has been known for over 2,000 years, it has only recently attracted the attention of medical researchers. But herpes, specifically HSV2, is just one of several sexually transmitted diseases (STDS) whose incidence has recently reached dramatic levels. This " new generation " of...

background: trichomoniasis is recognized as a major sexually transmitted disâ­ease (std) in the world and has the highest prevalence and incidence of std. the prevalence strongly is related to cultural and social norms in different socieâ­ties, in relation to sexual partnership, monogamy, or polygamy. our objective was to describe the frequency and natural history of infection and correlation o...

BACKGROUND In spite of sufficient knowledge about phenotypic variation of Trichomonas vaginalis, its genetic characteristics are poorly understood. We carried out a molecular epidemiology study in which in vitro metronidazole susceptibility of T. vaginalis isolates was considered. METHODS This study was conducted on 862 women admitted to Gynecology Clinics in Hamadan, west of Iran, during 201...

Trichomonas vaginalis is a common sexually transmitted protozoan parasite. Although often considered simply a nuisance infection, T. vaginalis has been implicated in premature rupture of placental membranes and increases in the risk of acquiring human immunodeficiency virus. Metronidazole, a 5-nitroimidazole, is currently the drug of choice to treat T. vaginalis infection. Because some patients...

Vaginal trichomoniasis, caused by Trichomonas vaginalis, is the most common sexually transmitted disease. More than 170 million people worldwide are annually infected by this protozoan. In the Republic of Korea, 10.4% of women complaining of vaginal symptoms and signs were found to be infected with T. vaginalis. However, despite its high prevalence, the pathogenesis of T. vaginalis infection ha...

Abstract Introduction Trichomoniasis is the most prevalent non-viral sexually transmitted infection (STI) in world, affecting ~4.1% of women and ~1.3% men aged 40–59 United States. Women with T. vaginalis are at 2- to 3-fold increased risk for acquiring human immunodeficiency virus (HIV). also associated vaginitis, pelvic inflammatory disease, post-hysterectomy cuff cellulitis other STIs. In ad...