BACKGROUND We studied the joint effect of baseline triglyceride and lipoprotein cholesterol levels on the incidence of cardiac end points in the trial group (n = 4,081) of the Helsinki Heart Study, a 5-year randomized coronary primary prevention trial among dyslipidemic middle-aged men. The relative risks (RR) were calculated using Cox proportional hazards models with a dummy variable technique...

In the current studies we describe the effects of PD 72953 and related compounds on lipoprotein levels in chow-fed male rats. After 2 weeks, 10 mg/kg of PD 72953 daily was as effective as 100 mg/kg gemfibrozil for elevating HDL-cholesterol. At 100 mg/kg, PD 72953 further elevated HDL-cholesterol to 232% of control levels, and was associated with increased HDL size and plasma apoE (169% of contr...

objective: dm is a major medical problem in developing countries such as iran. blood sugar and lipids levels increase in diabetics exacerbates the onset of diabetes mellitus (dm) late complications. researchers have focused on herbal medicines improve sugar and lipid levels against side decreasing effects and possible inefficacy of chemical drugs. this study has assessed the effect of curcumin ...

BACKGROUND Astaxanthin has been reported to improve dyslipidemia and metabolic syndrome in animals, but such effects in humans are not well known. METHODS Placebo-controlled astaxanthin administration at doses of 0, 6, 12, 18 mg/day for 12 weeks was randomly allocated to 61 non-obese subjects with fasting serum triglyceride of 120-200mg/dl and without diabetes and hypertension, aged 25-60 yea...

Dyslipidemia is implicated in increased cardiovascular risk associated with chronic kidney disease (CKD) and in the progression of renal damage. This study compared 4 different lipid-related ratios (total cholesterol [TC]/high-density lipoprotein cholesterol [HDL-C], triglyceride [TG]/HDL-C, calculated low-density lipoprotein cholesterol [c-LDL-C]/HDL-C, and non-HDL-C/HDL-C ratio) for predictio...

The influence of type fish consumption on cardiovascular risk profiles was studied in Sri Lankan community. Achallenge experiment set up to do a research the omega-3 fatty acid content cardiovascularrisk healthy people. Hundred undergraduates (subjects) who were between ages 23 30 yearsand full time resident hostels Lanka, randomly selected for this study. students fed with fishcurry and fried ...

We investigated the effects of estrogen and simvastatin, administered both alone and in combination, on the plasma lipid levels and lipoprotein-related enzymes in 45 postmenopausal women with type IIa hypercholesterolemia. They received 0.625 mg conjugated equine estrogen (n=15), 5 mg simvastatin (n=15), or the combination (n=15) daily for 3 months. We measured the concentrations of cholesterol...

  Purpose: Ascorbic acid has protective effects against coronary heart disease. These effects are   attributed to its antioxidant properties and its relation to plasma lipids. This study investigated the   effects of supplementing one gram of vitamin C per day on the serum serum lipoproteins of   healthy 18 to 55 years old individuals in Iran.   Materials and Methods: This study was conducted o...

Recombinant high density lipoprotein (rHDL) particles were prepared by cosonication of purified lipids and human apoproteins and incubated with partly purified cholesteryl ester transfer protein (CETP) and low density lipoprotein (LDL) containing [3H]cholesteryl ester. Increasing the triglyceride content relative to cholesteryl ester in rHDL significantly decreased the ability of the particles ...