The status of fasting triglycerides as a risk factor for coronary artery disease (CAD) has been considered weak because in multivariate analyses, triglycerides tend to be eliminated by high density lipoprotein (HDL) cholesterol. To further evaluate the role of triglycerides in CAD, we employed postprandial lipemia as a more informative means of characterizing triglyceride metabolism. In 61 male...

AIMS The aim was to review epidemiologic studies to reassess whether serum levels of triglycerides should be considered independently of high-density lipoprotein-cholesterol (HDL-C) as a predictor of coronary heart disease (CHD). METHODS AND RESULTS We systematically reviewed population-based cohort studies in which baseline serum levels of triglycerides and HDL-C were included as explanatory...

BACKGROUND Moderate hypertriglyceridemia is fairly common, and elevated triglycerides are a risk factor for coronary heart disease. The omega-3 fatty acids EPA and DHA have been shown to lower triglycerides in many clinical studies. Prescription omega-3 fatty acid concentrates (P-OM3) are indicated for use in people with very high triglycerides (> 500 mg/dl). Current guidelines recommend that t...

Triglycerides of toad bladder epithelium have been labeled in vitro with either palmitate-l-14C or linoleatel-14C, during incubation of bladders that had been cut in halves. Hydrolysis with pancreatic lipase of triglycerides labeled in this fashion revealed that palmitate-l-14C appeared predominantly in the 1and 3-position, whereas half of linoleate-l-14C was located in the 2-position. The hydr...

The parameters affecting the separation and quantification of triglycerides by gas-liquid chromatography have been investigated with the use of QF-1 and SE-30 as stationary phases and a flame ionization detector. The isothermal characteristics of a wide variety of triglycerides (carbon number 6 to 60) on both columns show that long retention volume is directly proportional to carbon number and ...

BACKGROUND Increased nonfasting plasma triglycerides marking increased amounts of cholesterol in remnant lipoproteins are important risk factors for cardiovascular disease, but whether lifelong reduced concentrations of triglycerides on a genetic basis ultimately lead to reduced all-cause mortality is unknown. We tested this hypothesis. METHODS Using individuals from the Copenhagen City Heart...