BACKGROUND & OBJECTIVES Subinhibitory concentrations (sub-MICs) of antibiotics, although not able to kill bacteria, but influence bacterial virulence significantly. Fluoroquinolones (FQs) which are used against other bacterial pathogens creates resistance in non-targeted Streptococcus pyogenes. This study was undertaken to characterize the effect of sub-MICs of FQs on S. pyogenes biofilm format...

In this paper, antibacterial activities of zinc oxide (ZnO) nanoparticles synthesized through green method using garlic bulb (Allium sativum), ginger (Zingiber officinale) extracts, and their mixture are reported. The ZnO NPs were characterized by X-ray diffraction (XRD), ultraviolet visible (UV–vis), photoluminescence (PL), spectroscopy Fourier transform infrared (FTIR) spectroscopy. crystalli...

BACKGROUND Understanding the distribution of disease in wildlife is key to predicting the impact of emerging zoonotic one health concerns, especially for wildlife species with extensive human and livestock interfaces. The widespread distribution and complex interactions of white-tailed deer (Odocoileus virginianus) with humans suggest deer population health and management may have implications ...

streptococcus pyogenes is one of the most important causes of bacterial pharyngitis. asymptomatic carriage of this organism especially among schoolchildren is a common issue. study of the prevalence and antimicrobial susceptibility pattern of the flora strains, as clinical indicators, are useful for treatment of streptococcal infections. the aim of this study was to determine the prevalence and...

background: in this study, erythromycin resistance isolates from the students with aged 12-15 yr old were studied and the mutations in the 23s rrna were identified by sequencing. methods: throat samples of 327 students with 12-15 years old from 3 schools of tehran were cultured on the selective strep­tococ­cus pyogenes medium and 23 strains were primarily selected as s. pyogenes . results: all ...

Virulent M protein-containing strains of Streptococcus pyogenes were found to adhere well to human pharyngeal cells in vitro. In contrast, an avirulent M - strain and an enteropathogenic Escherichia coli strain adhered feebly. When various rat tissues were exposed to mixtures of a virulent S. pyogenes strain and an enteropathogenic E. coli strain, the relative proportions of the two pathogenic ...

Tetracycline resistance is common among isolates of the animal commensal and opportunistic pathogen Arcanobacterium pyogenes. The tetracycline resistance determinant cloned from two bovine isolates of A. pyogenes was highly similar at the DNA level (92% identity) to the tet(W) gene, encoding a ribosomal protection tetracycline resistance protein, from the rumen bacterium Butyrivibrio fibrisolve...

BACKGROUND Infections in the oral and maxillofacial region can sometimes extend beyond the oral cavity, with serious consequences. Most oral infections are odontogenic, occurring through the root apex of the tooth or the periodontal pocket. It thus makes sense that edentulous patients have a much lower risk of oral bacterial infection. For this reason, while there are many reports on systemic i...

Serum opacity factor (SOF) is a protein expressed by Streptococcus pyogenes that opacifies mammalian serum. SOF is also a virulence factor of S. pyogenes, but it has not been previously shown to elicit a protective immune response. Herein, we report that SOF evokes bactericidal antibodies against S. pyogenes in humans, rabbits, and mice. Rabbit antiserum against purified recombinant SOF2 opsoni...

Purpose: To determine the anti-Streptococcus pyogenes activity of the chloroform extract of Boesenbergia pandurata (Roxb.) Schltr. (Zingiberaceae) and investigate its possible antibacterial mechanisms of action. Methods: Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were investigated against 47 clinical isolates of S. pyogenes. Time-kill study was pe...