The research investigated the possible antifungal behavior of forty-four truffles bioactive compounds conducted to investigate interaction modes these inhibitors against three different types fungal proteins: Candida albicans, Blastomyces dermatitidis, and Ganoderma microsporum. applied method in contrast ketoconazole griseofulvin revealed anti-fungal agents ergosterol, Catechin gallate rutin. ...