A compression-heat molding procedure was developed to fabricate poly(D,L-lactide-co-glycolide) (PLGA) controlled release drug delivery devices for the local treatment of tumors. The drug delivery devices were designed in the shape of a cylindrical millirod (1.6-mm diameter, 10-mm length), which allows them to be implanted by a modified 14-gauge tissue biopsy needle into tumor tissues via image-...

1. The density-gradient distribution patterns of acid phosphatase, Trypan Blue and denatured (125)I-labelled albumin were studied by discontinuous sucrose- and isopycnic sucrose-density-gradient centrifugation on combined heavy and light mitochondrial (M+L) fractions of liver isolated from normal rats and from rats injected with Triton WR-1339. 2. The results obtained from the subfractionation ...

The effect of L-glutamic acid on the embryolethal and teratogenic action of trypan blue was investigated in Wistar albino rats. L-glutamic acid was either incorporated into the diet, from gestation day 2 to day 20, or suspended in sesame oil and administered by gavage, from gestation day 6 to day 10. The day of finding sperm in the vaginal smear was designated day 0 of pregnancy. A teratogenic ...

Pregnant Wistar Albino rats were injected intraperitoneally with the thyroid stimulating hormone (TSH), obtained from several different suppliers, and with the dye trypan blue. Twenty USP units of TSH were injected on days 7 to 10 of pregnancy, one quarter of the total dose each day. Trypan blue was injected as a single subteratogenic dose (0.6 mg/100 gm maternal body weight) on day 8. Autopsy ...

BACKGROUND Enzyme based remediation of wastewater is emerging as a novel, efficient and environmentally-friendlier approach. However, studies showing detailed mechanisms of enzyme mediated degradation of organic pollutants are not widely published. RESULTS The present report describes a detailed study on the use of Soybean Peroxidase to efficiently degrade Trypan Blue, a diazo dye. In additio...

Significance: The development of an imaging technique to accurately identify biofilm regions on tissues and in wounds is crucial for the implementation precise surface-based treatments, leading better patient outcomes reduced chances infection. Aim: goal this study was develop that relies selective trypan blue (TB) staining dead cells, necrotic tissues, bacterial biofilms, wounds. Approach: exp...