Contemporary understandings of the epidemiology of Chagas disease as well as it’s clinical features, together with knowledge of the insect vectors and genotypes of the causal agent Trypanosoma cruzi are important pieces of information for comparisons with cases in the past. Evidence indicates that 4,000 years ago in northern Chile cases displaying digestive symptoms or ‘megacolon’ were frequent...

In this experiment, the effect o f betamethasone administered in the early postacute infection o f mice by Trypanosoma cruzi was studied. This drug was administered during 30 days after the 42nd day o f infection in a dose o f 0.15 mg/day. The betame­ thasone treatment did not cause fresh outbreaks o f parasitemia and the histopathological findings in the chronic phase were not different from t...

The current dataset is generated via bio-computational approach by surveying of INGI/RIME and SLACS CRE transposable elements (TEs) in latest update of Trypanosoma brucei genome. The distribution dataset (Supplementary File 1) shows the chromosome wise distribution of INGI/RIME and SLACS CRE transposable elements with the status of their -5' and -3' ends, genomic coverage and further elemental ...

We have previously described alterations in the cytoskeletal organization of heart muscle cells (HMC) infected with Trypanosoma cruzi in vitro. Our aim was to investigate whether these changes also affect the regulation of the actin mRNAs during HMC differentiation. Northern blot analysis revealed that alpha-cardiac actin mRNA levels increased during cell differentiation while beta-actin mRNA l...

In order to identify Trypanosoma cruzi reservoirs in transmission areas, 60 mammals in Capital and San Luis del Palmar Departments, Corrientes, Argentina were studied. Primates, rodents, carnivores, marsupials and edentates were investigated, 40 of them living in captivity and 20 caught with traps in a rural area. The mammals were examined by xenodiagnosis and third or fourth instars nymphs of ...

The prevalence of concurrent nematode-trypanosome infections in traditionally reared West African Dwarf sheep and goats in eastern Nigeria was monitored over a 12-month period during 1987-1988. The most prevalent nematodes were Haemonchus contortus and Trichostrongylus colubriformis, which usually occurred together in all nematode infected animals. Their combined prevalence rates ranged from 90...