OBJECT This study evaluated the efficacy of postoperative Gamma Knife surgery (GKS) to the tumor cavity following gross-total resection of a brain metastasis. METHODS A retrospective review was conducted of 700 patients who were treated for brain metastases using GKS. Forty-seven patients with pathologically confirmed metastatic disease underwent GKS to the postoperative resection cavity foll...

liposarcoma is a common malignant soft tissue tumor, accounting for 10% to 16% of all sarcomas. multicentric myxoid liposarcoma is an uncommon condition. differentiation between several primary tumors and metastasis of a single liposarcoma represents the main difficulty in diagnosis. a 47-years old woman presented with right thigh myxoid liposarcoma and underwent wide margin tumor resection. ot...

BACKGROUND The purpose of this study was to investigate the prognostic factors for salvage nasopharyngectomy. METHODS A retrospective review was conducted on maxillary swing nasopharyngectomy performed between 1998 and 2010. Univariate and multivariate analyses identified prognostic factors affecting actuarial local tumor control and overall survival. RESULTS The median follow-up duration w...

Renal cell carcinoma is an uncommon tumor in pediatric population.It is important for the clinicians to know its diagnosis as the management of renal cell carcinoma RCC is different from Wilms Tumor which is the most common tumor encountered in children .The management is surgical resection with no proven role for chemo or radiotherapy so far. Here, we present a case of seven-year-old male chil...

Although non-small cell lung cancer (NSCLC) with malignant pleural effusion (M1a) is generally contraindicated for surgery, several reports have demonstrated favorable prognosis. This study aimed to describe the results of surgical intervention in this disease. In this retrospective study, we evaluated NSCLC patients with ipsilateral malignant pleural effusion selected from Surveillance Epidemi...

myoepitheliomas are benign tumors which account for less than 1% of all salivary gland tumors. in this article, we report the clinical, pathologic, and immunohistochemical features of plasmacytoid myoepithelioma of the hard palate in a 73-year-old man having a painless hard palate mass with progressive growth for one month who was admitted in alzahra hospital of isfahan university of medical sc...

Background: The extent of tumor resection that should be undertaken in patients with GBM remains controversial. This study aims to clarify some independent predicting factors and to emphasis the role and the extent of tumor resection in increasing the survival of patients with GBM. Methods: We prospectively analyzed a cohort of 25 consecutive patients with histologically proven GBM who underwen...

BACKGROUND It is still under debate that whether stage IV colorectal cancer patients with unresectable metastasis can benefit from primary tumor resection, especially for asymptomatic colorectal cancer patients. Retrospective studies have shown controversial results concerning the benefit from surgery. This retrospective study aims to evaluate whether the site of primary tumor is a predictor of...

Despite continuing debates around cytoreductive surgery in malignant gliomas, there is broad consensus that increased extent of tumor reduction improves overall survival. However, maximization of the extent of tumor resection is hampered by difficulty in intraoperative discrimination between normal and pathological tissue. In this context, two established methods for tumor visualization, fluore...

Introduction: In recent years, the surgical management of angiofibroma has been greatly influenced by the use of endoscopic techniques. However, large tumors that extend into difficult anatomic sites present major challenges for management by either endoscopy or an open-surgery approach which needs new technique for the complete en block resection.   Materials and Methods: In a prospective obse...