despite many advances in the field of cancer treatment, intra-cranial tumor cases still have a poor prognosis. this research has been carried out in order to describe age and sex distributions and histopathological characteristics and site of intra-cranial tumors. we studied 425 patients with intra-cranial tumor whose samples were examined in pathology center of imam khomeini hospital from 1991...

introduction: meningioma is a benign and slowly-growing tumor that is responsible for 20% of brain neoplasms. it can be accompanied by some genetic disorders such as neurofibromatosis type 2 and is more common among women. as a space occupying lesion, it produces a wide range of signs and symptoms by compressing the adjacent and underlying tissues in the brain. trauma and viruses are possible e...

The role of exosomes and how they act at the tumour site are subjects growing study. These macrovesicles can be formed by a variety cell types, including immunological mesenchymal stem cells (MSCs). In particular, exosome synthesis tumor is crucial because these transported blood to distant organs enhance probability spread. Exosomes may have tumor-inhibiting effects depending on kind source, d...

statement of problem: chondrosarcoma is a tumor which includes 10 percent of the bone primary tumors. its prevalence is half of the osteosarcoma and two times of ewing’s. the mean age of the patients ranges between 30-50 years of old. there is no significant sex or race predilection. the most common complaint is the presence of a painless and enlarging mass. its clinical course is described as ...

background and objective: wilms’ tumor has been recognized as the most common primary malignancy of kidney at childhood, comprises 5-6% of tumors in this period, and manifests itself with various clinical symptoms. since there have been no sufficient studies in this field in iran, therefore, this study was conducted to investigate its histopathology and clinical symptoms. materials and methods:...

osteoid osteoma is a unique benign primary bone tumor that may present in the metaphyseal diaphyseal areas of the short tubular bones and has also been reported in the carpal bones. it occurs in the first two decades of life. the classic history is bone pain, often relieved by aspirin. the clinical appearance is local swelling and tenderness. the typical radiographic appearance is very characte...

the majority of osseous tumors of the hand are benign. the surgeon who evaluates and treats osseous tumors of the hand has to be familiar with limb anatomy, tumor biology, various presentations of the tumors and the range of treatment possibilities and their limitations. lesions in the hand more often present earlier in their course than those at other sites, just because they are more likely t...

Substantial experimental evidence has shown that dedifferentiation from an epithelial state to a mesenchymal-like state (EMT) drives tumor cell metastasis. This transition facilitates tumor cells to acquire motility and invasive features. Intriguingly, tumor cells at the metastatic site are primarily epithelial, and it is believed that they differentiate back to an epithelial state by a process...