The chemical structure of CyssTP and its self-assembly into a glutathione-activated carrier-free nanodrug triptolide (CyssTPN) as trackable drug delivery system for tumor therapy.

Modern cancer immunotherapies largely focus on the ability of CD8+ cytolytic T cells to directly recognize and kill tumor cells. These strategies are limited by development an immunosuppressive microenvironment emergence immune evasive MHC-deficient or IFN-unresponsive CD4+ effector can contribute responses independent However, potential mechanisms cell-mediated anti-tumor immunity remain elusi...

 Abstract Liver neoplasm is not an uncommon disease in Asian countries. Liposarcoma is a rare mesenchymal malignant tumor which usually originates in the retroperitoneum and extremities. From 1973 till now about 10 cases of primary liver liposarcoma have been reported. We present the eleventh case in a young adult female with uncommon presentation. She suffered from a huge mass in the right por...

Microwave Ablation 2,2′-Azobis(2-[2-imidazolin-2-yl]propane) dihydrochloride (AIPH)-loaded temperaturesensitive liposomes can be well accumulated in the tumor site after intravenous injection. In article 2202947 by Hu Peng, Zhengbao Zha, and co-workers, when is exposed to environment of microwave thermal ablation, release loaded AIPH decomposes produce cytotoxic free radicals. Tumor growth effe...

Photodynamic Therapy In article number 2100789 by Jinsheng Shi, Xiaoying Kong, and co-workers, the combined strategy of UCRSPH SA CaO2 nano platform achieves application self reinforcing PDT, Ca2+ ion interference therapy multi means in situ imaging diagnosis treatment tumors, which is great significance for improving clinical therapeutic effect tumors precise tumor vivo.

Giant chorioangioma is a placental tumor associated with gestational complications such as preeclampsia, polyhydramnios and hemorrhage. In addition, this tumor might lead to the incidence of non-immune fetal hydrops, heart failure, anemia, thrombocytopenia, weight loss and death among neonates. In this case report, the clinical image of a term newborn (weighing 2800 g) with one-minute Apgar sco...