BACKGROUND & OBJECTIVES The impact of several environmental and genetic factors on diabetes is well documented. Though the association between the vitamin D receptor (VDR) gene polymorphisms and type 2 diabetes mellitus (T2DM) has been analyzed in different ethnic groups, the results have been inconsistent. The aim of this study was to evaluate the possible association between VDR FokI polymorp...

Sulfonylureas are commonly used for the treatment of patients with type 2 diabetes mellitus (T2DM). However, some clinical concerns regarding their use have grown over the past decade. Thus, results of a previous Japan-wide cross-sectional survey of patients with type 2 diabetes mellitus (T2DM) were analyzed to determine the present status and problems associated with the use of sulfonylureas i...

RATIONALE The impact of diabetes mellitus on bone marrow (BM) structure is incompletely understood. OBJECTIVE Investigate the effect of type-2 diabetes mellitus (T2DM) on BM microvascular and hematopoietic cell composition in patients without vascular complications. METHODS AND RESULTS Bone samples were obtained from T2DM patients and nondiabetic controls (C) during hip replacement surgery ...

BACKGROUND Comorbid depression in diabetes has been suggested as one of the possible causes of an inadequate glycemic control. The purpose of this study was to investigate the association between major depression and the glycemic control of type 2 diabetes mellitus (T2DM). METHODS Seventy T2DM patients were evaluated. They underwent a psychiatric examination using the following instruments: S...

BACKGROUND To date, few administrative diabetes mellitus (DM) registries have distinguished type 1 diabetes mellitus (T1DM) from type 2 diabetes mellitus (T2DM). OBJECTIVE Using a classification tree model, a prediction rule was developed to distinguish T1DM from T2DM in a large administrative database. METHODS The Medical Archival Retrieval System at the University of Pittsburgh Medical Ce...

introduction High‐risk population of Type 2 diabetes mellitus (T2DM) includes both euglycemic (normal glucose tolerance [NGT]) population with high risk of diabetes (EPWHROD) and prediabetic population. Between these two groups, prediabetic people have a higher chance to develop diabetes. Prediabetes is associated with increased risk of atherosclerotic cerebrocardiovascular disease (ASCCVD), di...

conclusions the findings confirmed the positive influence of ud supplements and aerobic training on glycemic control in males with t2dm. when aerobic training was combined with a ud supplement, a greater degree of glycemic control was observed. results a significant decrease in fasting blood sugar (fbs) was observed in the ae group (-9.50 ± 6.96 mg/dl; p = 0.002), the ud group (-7.60 ± 6.04 mg/...

Objective: Type 2 diabetes mellitus (T2DM) is a chronic condition that requires consistent medical care to help control glycemic indices. Diabetes self-management is found to be essential for optimal glycemic control. This study aimed to investigate the predictors of diabetes self-management in adult with T2DM. Materials and Methods: A cross-sectional study was conducted. A purposive sample of...

PURPOSE This study was carried out to investigate the effects of different training modes on IL-6 and CRP in patients with type 2 diabetes mellitus (T2DM). METHODS The subjects consisted of 16 middle-aged women with type 2 diabetes mellitus (T2DM), all of whom had no other complications. The 16 subjects were randomly assigned to two experimental groups: the circuit training group (CTG, n = 8)...

Background: Lifestyle intervention is effective in preventing type 2 diabetes mellitus (T2DM). The efficacy of components across different sociocultural settings relevant for real world implementation. Thus, this study aimed to evaluate the effectiveness a culturally tailored prevention program (CTDPP) at-risk Muslim people Thailand.