PURPOSE The global spread of bla CTX-M-I extended-spectrum beta-lactamase (ESBL)-producing Salmonella spp. remains a major threat to treatment and control. Evidence of emergence and spread of this marker are lacking in Nigeria. This study investigated bla CTX-M-I ESBL production among Salmonella isolates from hospitalized patients. METHODS Patients (158 total) made up of two groups were evalu...

Non typhoidal Salmonellae spp. causes clinical symptoms especially in neonates, infants, aged and immunocompromised patients. Hematogenous dissemination may occur in complicated cases whereas the formation of abscess is rare. A 61-year old woman presented to our hospital with pain and a mass in her left arm, without fever and leukocytosis. She was using methotrexate, corticosteroids and quinine...

Human immunodeficiency virus type 1 (HIV-1) infects and kills T cells, profoundly damaging the host-specific immune response. The virus also integrates into memory T cells and long-lived macrophages, establishing chronic infections. HIV-1 infection impairs the functions of macrophages both in vivo and in vitro, which contributes to the development of opportunistic diseases. Non-typhoidal Salmon...

Invasion of the central nervous system is a severe and frequently fatal event during the course of many infectious diseases and those who survive are often left with permanent neurological dysfunction. Non typhoidal Salmonella commonly cause invasive bacterial infections in children associated with high mortality. A 20 day old female child was admitted to neonatal intensive care unit with the s...

Typhoid fever is an endemic disease that has been acknowledged as a major global health burden. neglected re-emerging infectious transmitted through fecal oral route. Nevertheless, non-typhoidal Salmonella outbreak increasing globally with large number of cases involving immunocompromised individuals. The clinical diagnosis typhoid difficult due to the overlapping symptoms fever, Salmonella, an...