subunits that always include one or more homologues of Ulrich Gohlke, Antony Warne and the mitochondrially coded eukaryotic proteins (Saraste, Matti Saraste 1990). European Molecular Biology Laboratory, Biological Structures The Gram-negative eubacterium Escherichia coli posProgramme, Meyerhofstrasse 1, Postfach 10.2209, sesses a branched respiratory chain. Depending on the D-69012 Heidelberg, ...

Ubiquinone (UQ) is a lipophilic compound present in most living organisms, where UQ's interesting but complex electrochemistry serves an important role the transfer of electrons and protons within across mitochondrial membrane. We briefly review electrochemical characteristics UQ its reduced state, ubiquinol, solution immobilized on electrodes, together with application sensing detection system...

This article provides an updated overview of the plethora of complex I inhibitors. The inhibitors are presented within the broad categories of natural and commercial compounds and their potency is related to that of rotenone, the classical inhibitor of complex I. Among commercial products, particular attention is dedicated to inhibitors of pharmacological or toxicological relevance. The compoun...

The plant mitochondrial protein alternative oxidase catalyses dioxygen dependent ubiquinol oxidation to yield ubiquinone and water. A structure of this protein has previously been proposed based on an assumed structural homology to the di-iron carboxylate family of proteins. However, these authors suggested the protein has a very different topology than the known structures of di-iron carboxyla...