BACKGROUND The aim of this study was to assess if FDG-PET could guide dose prescription heterogeneity and decrease arbitrary location of hotspots in SBRT. METHODS For three patients with stage I lung cancer, a CT-simulation and a FDG-PET were registered to define respectively the PTVCT and the biological target volume (BTV). Two plans involving volumetric modulated arc therapy (VMAT) and simu...

ATP-sensitive potassium (KATP) channels couple cell metabolism to electrical activity by regulating K+ flux across the plasma membrane. Channel closure is mediated by ATP, which binds to the pore-forming subunit (Kir6.2). Here we use homology modelling and ligand docking to construct a model of the Kir6.2 tetramer and identify the ATP-binding site. The model is consistent with a large amount of...

PURPOSE To investigate the blood pressure responses during recovery after two protocols of circuit resistance exercises (CRE) with different rest intervals (RI). METHODS Eleven normotensive males (aged 19.5 ± 1.0 yrs, height 172.8 ± 5.7 cm and weight 65.1 ± 8.1 kg) performed two CRE with RI of 30 (RI30s) and 40 (RI40s) seconds between the exercises randomly, as well as a control session witho...

The analysis of white blood cells, which defend the body against deadly infections and disease-causing substances, is an important issue in medical world. concentrations these cells blood, examined 5 classes, i.e. monocytes, eosinophils, basophils, lymphocytes, neutrophils, vary according to types diseases body. peripheral smear widely used analyze cells. Manual evaluation this method laborious...

Endodontic treatment is based on an understanding of the internal anatomy, which facilitates precise exploration canals. The present study aimed to report a clinical case referring endodontic upper left second molar, presenting mesiopalatal canal and communication with periodontal tissues in distal region pulp chamber, furcation region, due dental caries. 41-year-old patient did not any systemi...

PURPOSE Stereotactic body radiotherapy (SBRT) is an established treatment technique in the management of medically inoperable early stage non-small cell lung cancer (NSCLC). Different techniques such as volumetric modulated arc (VMAT) and three-dimensional conformal arc (DCA) can be used in SBRT. Previously, it has been shown that VMAT is superior to DCA technique in terms of plan evaluation pa...