Background & Aim: Homalium letestui Pellegr (Flacourtiaceae) used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases was evaluated for antiulcer properties.  Experimental: The effects of ethanol stem extract of H. letestui (200 – 600 mg/kg) and fractions (Aqueous and Dichloromethane, 400 mg/kg) on experimentally in...

Prevalence of helicobacter pylori was evaluated by urease test in 513 patients undergoing GI endoscopy, in hospital No1 Kerman university of medical sciences and health services from June 1992 through April 1993. H. Pylori was detected in 56.9℅ of tested samples by urease test. There was no significant correlation with sex, age and cigarette smoking. Prevalence of H.pylori was 16℅ in control gr...

gastric ulcer is one of the most prevalent gastrointestinal (gi) disorders, which affects approximately 5-10% of people during their life. in recent years, plentiful works have been carried out on herbal medicine to clarify their potential efficacy in gastric ulcer prevention or management. tripleuro-spermum disciforme is one of the indigenous plants that is readily available and has been tradi...

Stomal Ulceration Stomal ulceration may follow anastomosis of the stomach to any other part of the alimentary canal. I have indicated in my first lecture that by I954, stomal ulceration had followed in over 50 per cent. of the cases in which I had carried out a gastrojejunostomy for duodenal ulcer in I943. In such cases at the second operation, the duodenal ulcer, although often reported as act...

In Central Europe and in South Africa duodenal ulcer disease has been reported to occur twice as often in migrant workers as in the indigenous population. To investigate the reasons for this phenomenon the joint effect of occupation and nationality on the prevalence of gastric and duodenal ulcer was studied in a survey of 73,000 active members of the German workforce. Non-ulcer dyspepsia and ga...

In normal, duodenal ulcer, and gastric ulcer subjects the two main forms of gastrin, G17 and G34, were estimated by radioimmunoassay in fasting serum and after feeding. Two antisera were used: one showing high specificity for G17, the other specific for the common COOH-terminus of G17 and G34 and so allowing estimation of G34 by difference. Basal G17 was similar in gastric ulcer, duodenal ulcer...

Systematic studies of psychiatric disorders in non -ulcer dyspepsia are rare. The aim of the present study was to find out the nature and prevalence of psychiatric morbidity in non-ulcer dyspepsia. Thirty three patients with non-ulcer dyspepsia and thirty with duodenal ulcer were assessed for psychiatric morbidity with the help of the regular version of the SADS, and diagnosed according to DSM-...

The augmented histamine test has been widely accepted as an accurate and reproducible means of measuring the secretory capacity of the stomach. It would appear that histamine requires the cooperation of cholinergic mechanisms to produce a full secretory response. Payne and Kay (1962) showed that the withdrawal of vagally released acetylcholine was mainly responsible for the large reduction in t...

An ideal operation for a benign disease, such as duodenal ulcer, must be effective, relatively free of serious postoperative complications and standardized for effective performance. Highly selective vagotomy, an operation known to have few side effects, has not been adopted by many surgeons because of the concerns about postoperative recurrent ulcers, as well as by concerns about the technical...