Abstract Two widely used active pharmaceutical ingredients (API), ambroxol hydrochloride (AMB·HCl) and bromhexine (BMH·HCl), belong to the expectorant mucokinetic group of drugs. Their applications are found in treatment upper respiratory tract bronchopulmonary diseases. The compounds have similar chemical structures, but different enough distinguish their physicochemical properties. To underst...

A quantitative description of droplet evaporation is important to aerosol research for nanofabrication, spray drying, fuel combustion, pollution control, and respiratory medical treatments. Evaporation is a movingboundary problem with coupled mass and heat transport. An explicit finite-difference methodology and computer code has been developed for simulation of an evolving droplet, property da...

The extension of the translated–consistent Peng–Robinson (tc-PR) equation state (EoS) to mixtures has been investigated. For this purpose, advanced EoS/aresE,? mixing rules are used combine tc-PR EoS with residual part an activity coefficient model chosen among Wilson, nonrandom two-liquid (NRTL), and universal quasi-chemical (UNIQUAC) models. performances three resulting versions compared agai...

A method based on the Genetic Algorithm (GA) was developed to study the phase behavior of multicomponent and multiphase systems. Upon application of the GA to the thermodynamic models which are commonly used to study the VLE, VLLE and LLE phase equilibria, the physically meaningful values for the Binary Interaction Parameters (BIP) of the models were obtained. Using the method proposed in this ...

Çözücü ve çözücü karışımları birçok sanayii dalında yaygın olarak kullanılmaktadır. Çözücüler arasında esterler alkollerin endüstriyel bilimsel önemi nedeniyle bunların ikili üzerine çok sayıda araştırma yapılmıştır. Asetik asidin Fischer esterleştirme reaksiyonu etanol dehidrojenasyon yöntemiyle üretilebilen önemli bir olan etil asetat kimya endüstrisinde Etil tüm bileşimlerde ile karışabilen ...

There is a growing interest in the search of clean, sustainable and renewable energy sources. Among them, the use of bio-diesel from vegetable oils is being considered. The knowledge of the phase equilibrium in mixtures found in the bio-diesel production is essential for the correct design and operation of the process. However, there is still a lack of information about the parameter values for...

the purpose of this reaserch is to measure the phase equilibrium data of the ternary system (water + phosphoric acid + 1-nonanol) at different temperatures. experimental solubility curves and tie-line points for the system were obtained at t = 298.2, 308.2 and 318.2 k and ambient pressure. the binodal curve data were detected by the cloud point method. the mass fractions of each layer were achi...