Acid inhibitory therapy has long been considered of no benefit for upper GI bleeding. The reason was that achlorhydria in the stomach could not be achieved with any single or combination of acid inhibitory drugs. The introduction of proton pump inhibitors has, for the first time, allowed the physician to temporarily achieve achlorhydria by large doses of intravenously applied proton pump inhibi...

* Corresponding Author: Maryam Moini, MD Gastroenterology and Hepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Telefax: + 98 711 6473236 Email: [email protected] Received: 10 Jan. 2013 Accepted: 11 Mar. 2013 A 50-year-old lady presented with bloody vomiting and melena since four days prior to admission. Her medical history was significant only for hypertension wh...

Aims and Objective: Comparative study of hepatic changes in patients of metabolic syndrome and chronic alcoholism. Material and Method: The material of the study included 30 metabolic syndrome patients and 30 chronic alcoholics selected from the medicine outdoor clinic (including diabetic clinic) and medicine indoor wards as well as from GI clinic of Postgraduate Department of Medicine, S.N. Me...

In this editorial, I refer to the relative risks associated with different interventions. To provide a perspective of what it means, please consider the risks of particular events in the placebo group of controlled trials of cyclooxygenase-2 inhibitors: major vascular events (0.82%) including nonfatal myocardial infarction (MI; 0.29%) or any MI (0.33%), any stroke (0.36%), heart failure (0.26%)...

Gastric antral vascular ectasia (GAVE) is a rare clinical disease which can cause recurrent upper gastrointestinal (GI) tract bleeding. It is responsible for about 4% of non-variceal upper GI haemorrhages. As one of the vascular diseases that happened in stomach, GAVE was also named as watermelon stomach (WS) for its characteristic endoscopic performance. Compared with portal hypertensive gastr...

background and objective: to assess the incidence and risk factors of upper gastrointestinal bleeding in children admitted to pediatric intensive care unit for more than 6 hrs. methods: we prospectively collected medical records of children between 1 month and 18 years old admit-ted to our 10 bed picu of a tertiary care university hospital between december 1, 2014 and may 30, 2015. de-mographic...

BACKGROUND/AIMS The risk of gastrointestinal (GI) bleeding with dabigatran when compared to warfarin has been controversial in the literature. The aim of our study was to assess this risk with the use of dabigatran. METHODS We examined the medical records of patients who were started on dabigatran or warfarin from October 2010 to October 2012. The study was conducted in two hospitals. RESUL...

A 53 year-old Caucasian man with no previous history of gastrointestinal bleeding presented with sudden, massive hematochezia and abdominal pain; his hemoglobin dropped from 12 to 8.3. Colonoscopy revealed coagulated blood in a diverticulum, but bleeding recurred after cautery of the lesion.Repeated upper and lower gastrointestinal (GI) endoscopy, visceral selective angiogram, bleeding scan, an...

objective: whole-mouth examination is generally considered as a gold standard for exact periodontal disease assessment. partial mouth examination also has sometimes been used for this purpose, but its efficacy has been questioned. with regard to symmetric destruction hypothesis of periodontal disease, the present study investigated the efficacy of partial- mouth examination as an alternative fo...

A case of massive upper gastrointestinal bleeding in a 37-year-old female is presented showing a submucosal mass in the gastric body. At laparotomy a pedunculated submucosal mass was found located on the posterior wall at the junction of the body and antrum of the stomach, 8 cm from the pylorus. Pathology confirmed that it was a 4 cm benign gastric lipoma with a bleeding central ulcer. Gastric ...