OBJECTIVE To evaluate the impact of onabotulinumtoxinA on individual domains of the quality of life questionnaires in a pooled analysis of two phase 3 trials in overactive bladder patients with urinary incontinence who were inadequately managed by ≥1 anticholinergic. METHODS Patients received intradetrusor injections of onabotulinumtoxinA 100U (n = 557) or placebo (n = 548). The proportions o...

BACKGROUND Critically ill patients including trauma patients are at high risk of urinary tract infection (UTI). The composition of urine in trauma patients may be modified due to inflammation, systemic stress, rhabdomyolysis, life support treatment and/or urinary catheter insertion. METHODS Prospective, single-centre, observational study conducted in patients with severe trauma and without a ...

The urinary tract is a major site of nosocomial infections (4, 5). The leading cause of nosocomial urinary tract infections is urinary catheterization which, in turn, is the most common predisposing factor for fatal gram-negative sepsis in hospitals (6). A recent publication suggested that catheters coated with silver powder and containing a silver-plated connector could protect patients from c...

BACKGROUND Controlling urinary tract infections (UTIs) associated with intermittent catheterization in geriatric patients. AIM After a local epidemiological study identified high rates of UTI, a multi-disciplinary working group implemented and evaluated corrective measures. METHODS In 2009, a one-month prospective study measured the incidence of UTI, controlled for risk factors and exposure...

The goal of this review article is to discuss the etiology of recurrent urinary tract infections (UTIs) in individuals with impaired bladder emptying, evaluate existing studies regarding UTI prevention strategies in this population, and explore the published experiences with intravesical therapy for the prevention and treatment of recurrent UTIs in patients performing clean intermittent cathete...

: Urinary tract infection is the second most common bacterial and themost disease that affects urinary system.

BACKGROUND Indwelling urinary catheters are used postoperatively in hip fracture care. Their use beyond the immediate postoperative period may result in excess nosocomial infections. OBJECTIVES The objectives of this study were to explore the relationship between extended indwelling urinary catheterization and outcomes for patients sustaining hip fracture discharged to skilled nursing facilit...

We evaluated the available literature on effectiveness of silver-coated versus uncoated catheters for the prevention of urinary tract infections in catheterized patients stratified by sex, systemic antibiotic use, renal function and duration of catheterization. Controlled clinical trials, randomized clinical trials and systematic reviews/meta-analysis were identified by a search strategy in Med...

Purple urine bag syndrome (PUBS) is a unique disease entity characterized by an alarming purple discoloration of the urine secondary to recurrent urinary tract infections with indigo- and indirubin-producing bacteria. It is usually associated with prolonged urinary catheterization and chronic debilitated states. We hereby present a concise review of this rare phenomenon with historic perspectiv...