Ö o ( c p e fi ( ( t d v ( l With the advent of the Starr-Edwards mechanical mitral and aortic valves in the 1960s, the surgical era of the treatment of cardiac valvular disease began in earnest. Although considered definitive, valve replacement surgery effectively represents an exchange of the pathophysiology of severe valvular dysfunction for the diseases and complications associated with pro...

Twelve patients with aortic insufficiency (AI) were investigated by echocardiographic methods using reflected ultrasound. No patients with associated mitral valvular disease were included. Estimates of each patient's aortic valvular total flow (QAt) as computed from left ventricular cavity minor-axis dimension changes at end-diastole (Dd) and end-systole (D,) were compared with their respective...

Twelve patients with aortic insufficiency (AI) were investigated by echocardiographic methods using reflected ultrasound. No patients with associated mitral valvular disease were included. Estimates of each patient's aortic valvular total flow (QAt) as computed from left ventricular cavity minor-axis dimension changes at end-diastole (Dd) and end-systole (D,) were compared with their respective...

METHYSERGIDE, an anti-serotonin agent used for prophylaxis of migraine headaches, produces mitral and aortic valvular fibrosis resulting in valvular dysfunction. '-7 This study reports a unique case both of hemodynamically significant right-sided valvular disease and of intramyocardial fibrosis (diagnosed by transvenous cardiac biopsy) resulting from methysergide administration. Our patient rep...

Valvular heart disease (VHD) is a clinically important diagnosis, with significant associated morbidity and mortality. Multiple imaging modalities exist to characterize valvular and associated cardiac anatomy. Cardiovascular magnetic resonance (CMR) has emerged as a comprehensive noninvasive imaging modality for VHD. With use of well-established, standardized imaging sequences, CMR can accurate...

BACKGROUND Valvular heart disease, including rheumatic heart disease (RHD), is an important cause of heart disease globally. Management of advanced disease can include surgery and other interventions to repair or replace affected valves. This article summarises the methodology of a study that will incorporate enhanced data collection systems to provide additional insights into treatment choice ...

Valvular heart disease is common in systemic lupus erythematosus (SLE) and antiphospholipid syndrome. Immunologic insult plays a fundamental role in its pathogenesis but data on the role of antiphospholipid antibodies have been inconsistent, particularly regarding SLE-associated valvular lesions. Although timely diagnosis is essential to prevent progression of valvular lesions, treatment remain...

Background Accurately measuring blood flow with CMR is paramount in patients with valvular disease. These flow measurements are important components of a CMR report and provide the referring clinicians with valuable information in which to base further clinical management. This poster presents a guide on how to measure blood flow accurately based on our experience at the Bristol Heart Institute.

The following valvular disorders are considered here in the context of competitive athletes: mitral stenosis (MS), mitral regurgitation (MR), aortic stenosis (AS), aortic regurgitation (AR), tricuspid regurgitation (TR), tricuspid stenosis, and multivalvular disease. Recommendations are also provided for patients who have undergone valve repair or replacement. The diagnosis of valvular heart di...

BACKGROUND Carcinoid heart disease is a rare form of valvular heart disease. We sought describe the spectrum of carcinoid heart disease identified by echocardiography and cardiac MRI. METHOD AND RESULTS Two hundred fifty-two patients with carcinoid syndrome underwent a range of investigations including 2D transthoracic echocardiography, 3D transthoracic echocardiography and transesophageal ec...