Hereditary haemorrhagic telangiectasia (HHT) is a genetically heterogeneous dominant disorder. Two disease loci have been mapped to chromosomes 9q3 and 12q. In a large pedigree, with an unusually high number of patients with liver vascular malformations, both previously mapped loci have been excluded. The loci for two other inherited vascular malformation diseases, cerebral cavernous malformati...

Benign hemangiomas and vascular malformations are the most common tumor of infants and children [1]. Skull involvement is rare compared with soft-tissue involvement. A plethora of classifications applied to these lesions has led to an imperfect and suboptimal understanding of them. Burrows et al. [2] describe angiographic differences between hemangiomas and vascular malformations that corrobora...

Vascular anomalies are localized defects of the vasculature, and usually affect a limited number of vessels in a restricted area of the body. They are subdivided into vascular malformations and vascular tumours. Most are sporadic, but Mendelian inheritance is observed in some families. By genetic analysis, several causative genes have been identified during the last 10 years. This has shed ligh...

Verrucous hemangiomas (VH) are uncommon, congenital vascular malformations of the cutaneous and subcutaneous tissues that spare the deeper subfacial structures. VH usually presents at birth and slowly grows with age. It usually presents as hyperkeratotic, scattered, bluish-red plaques or nodules of various sizes. Although the lesions mostly have a linear pattern, serpiginous and reticulat...

Small vascular malformations of the brain have been increasingly often recognized in recent years as possible sources of intracranial hemorrhage, especially in young people (1-6). There are many other problems in connection with these lesions. It is the purpose of this paper to illustrate hy means of case studies some of the local results of these malformations and also to discuss the multiple ...