BACKGROUND Ventilator-associated pneumonia (VAP) is considered to be an important cause of infection-related death and morbidity in intensive care units (ICUs). We sought to determine the long-term effect of an educational program to prevent VAP in a medical ICU (MICU). METHODS A 4-year controlled, prospective, quasi-experimental study was conducted in an MICU, surgical ICU (SICU), and corona...

BACKGROUND Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransferase is an enzyme that is highly upregulated in ventilator-induced lung injury and exacerbates the injury when given exogenously. Nicotinamide (vitamin B3) directly inhibits downstream pa...

conclusions the study showed that hais were more frequent in elderly population predominately with respect to vap and infections by gram-negative pathogens. overall mortally was greater in the elderly group although the odds ratio for death was higher in younger patients and increased with every hai diagnosed. patients and methods retrospective analysis of all hospital-acquired infections (hais...