PURPOSE The role of microglia, present in the retina early in development before vascularization, remains ill defined. The authors investigated whether microglia are implicated in retinal blood vessel formation. METHODS The microglia and vasculature of developing human fetal and rodent retinas were examined by labeling the endothelial cells with lectin and the microglia with CD18 antibody or ...

Lymph node metastasis is an important prognostic factor in gastric cancer. Vascular endothelial growth factor-D (VEGF-D) is a lymphangiogenic growth factor that activates VEGF receptor (VEGFR)-3, a receptor expressed in the lymphatic endothelium. We investigated the clinical value of VEGF-D expression and VEGFR-3 positive vessel density in gastric carcinoma with regard to lymphangiogenesis. Imm...

localizing the optic disc (od) in retinal fundus images is of critical importance, since it is very similar to hard exudates (found in pathology) in color and brightness. because of the importance of od localization in clinical applications, many techniques have been developed. in this paper, we present the results obtained from two methods, correlation and least square, to approximate the opti...

coronary artery anomalies are rare, with their incidence varying from 1 to 5%. angiography is a commonly used modality for the assessment of coronary artery anomalies. based on previous reports, a majority of coronary artery anomalies are of origin or distribution, with separate ostia of the left anterior descending artery and left circumflex artery. coronary artery anomalies may cause myocardi...

anomalous origin of the left coronary artery from the pulmonary artery (alcapa) is a rare congenital cardiac malformation. we report three cases of alcapa who survived to adulthood. the first case was a 51-year-old woman who complained of typical chest pain that was diagnosed with alcapa using cardiac catheterization and coronary computed tomographic angiography (cta). the second case was a 30-...

BACKGROUND AND PURPOSE Although studies have evaluated the differential imaging of moyamoya disease and atherosclerosis, none have investigated the added value of vessel wall magnetic resonance imaging (MRI). This study evaluates the added diagnostic value of vessel wall MRI in differentiating moyamoya disease, atherosclerotic-moyamoya syndrome (A-MMS), and vasculitic-MMS (V-MMS) with a multico...

Involvement of brain parenchyma or meninges in ANCA-associated small-vessel vasculitis such as Wegener's granulomatosis (WG) is not uncommon. In contrast, involvement of the pituitary is exceedingly rare with only a few cases reported so far. The diagnosis is usually made on the basis of imaging techniques and abnormal pituitary function tests in the setting of active systemic vasculitis. Howev...

We describe a case of an adolescent male with Henoch-Schonlein purpura (HSP), presenting with cutaneous and gastrointestinal manifestations. Endoscopy revealed diffuse ulcerations in the stomach, duodenum, and right colon. Biopsies revealed a leukocytoclastic vasculitis in the skin and gastrointestinal tract. Steroid therapy led to complete resolution of the symptoms. HSP is the most common chi...

Objectives: Despite widespread use of smokeless tobacco (ST) in Pakistan, a very limited empirical evidence have been reported regarding its impact on the coronary anatomy and obstructions. Therefore, this study was conducted to compare angiographic profile users smokers with non-tobacco presented acute myocardial infarction (AMI). Methodology: Consecutive patients AMI were stratified four grou...

Pressure vessel is a container used to store fluids under pressure and temperature. The fluids can be air, water, chemicals, fuel, gases etc. are most commonly used in food and chemical industries, oil refineries and so on. Pressure vessel is subjected to thermal and structural loads for power plant applications. Since the pressure vessel are subjected to both structural and thermal loads stres...