AIM To evaluate the characteristics that are associated with successful transition to school outcomes in preschool aged children with autism. METHODS Twenty-one participants transitioning from an early intervention program were assessed at two time points; at the end of their preschool placement and approximately 5 mo later following their transition to school. Child characteristics were asse...

Cognitive functioning has historically been used to predict adaptive outcomes of people with autism spectrum disorders; however, research shows that it is not a complete predictor. The current study explored whether emotion perception was a predictor of adaptive outcomes, and more specifically, hypothesized that emotion perception (Diagnostic Analysis of Nonverbal Accuracy-2 error scores) would...

Funding: This research was supported by grants from the Simons Foundation (SFARI#383660 and #641201) NIH (PO1 HD 64653 P50 DC 13027) to HTF. Conflict of Interest: The authors declare that they have no conflict interest. Information about ELSA can be found on our website, https://sites.bu.edu/elsa/ , is not a commercially available product. Corresponding Author: Mihaela Barokova, M.A., Departmen...

BACKGROUND Prenatal exposure to alcohol often results in disruption to discrete cognitive and behavioral domains, including executive function (EF) and adaptive functioning. In the current study, the relation between these 2 domains was examined in children with histories of heavy prenatal alcohol exposure, nonexposed children with a diagnosis of attention-deficit/hyperactivity disorder (ADHD),...

BACKGROUND AND PURPOSE Dravet syndrome is a rare and severe type of epilepsy in infants. The heterogeneity in the overall intellectual disability that these patients suffer from has been attributed to differences in genetic background and epilepsy severity. METHODS Eighteen Vietnamese children diagnosed with Dravet syndrome were included in this study. SCN1A variants were screened by direct s...

Background: Congenital adrenal hyperplasia (CAH) is a genetic problem of steroidogenesis in adrenals. Due to a particular enzyme deficiency causing lack of steroids, negative feedback involving hypothalamic-pituitary-adrenal axis is lost. This would result in increased production of adrenocorticotrophic hormone and corticotropin-releasing hormone which may have their effects on learning and mem...

OBJECTIVE To examine the neurobehavioral status of children with traumatic head injury (THI) and to identify variables that predict outcome. DESIGN Retrospective chart review, with follow-up 1-5 years after injury. Outcome predictor variables were identified through stepwise regression analysis. SETTING Level one trauma center and pediatric rehabilitation program. PATIENTS 71 Children wit...

The PEP-R (psychoeducational profile revised) is an instrument that has been used in many countries to assess abilities and formulate treatment programs for children with autism and related developmental disorders. To the end to provide further information on the PEP-R's psychometric properties, a large sample (N = 137) of children presenting Autistic Disorder symptoms under the age of 12 years...

IMPORTANCE The finding of factors that differentially predict the likelihood of response to placebo over that of an active drug could have a significant impact on study design in this population. OBJECTIVE To identify possible nonspecific, baseline predictors of response to intervention in a large randomized clinical trial of children and adolescents with autism spectrum disorders. DESIGN, ...

OBJECTIVE Low birth weight (LBW; below 2500 grams) is a general risk factor for a variety of neurodevelopmental difficulties. However, these children may remain more vulnerable to neurologic and environmental insults occurring years later. This prospective case series reports on children who sustained a mild, moderate, or severe traumatic brain injury (TBI) in middle childhood but who had also ...