To evaluate the role of human bocavirus (hBoV) as a causative agent of respiratory disease, the importance of the viral load in respiratory disease type and severity and the pathogenicity of the different hBoV species, we studied all hBoV-positive nasopharyngeal samples collected from children who attended an emergency room for a respiratory tract infection during three winters (2009-2010, 2011...

BACKGROUND Viral respiratory infections are associated with nearly 80% of asthma exacerbation episodes. These can have severe adverse outcomes in patients with established asthma. AIM The aim of the study was to identify the viral causes of acute respiratory infection that precipitate acute asthma exacerbation in Egyptian asthmatic children. PATIENTS AND METHODS The current prospective stud...

Respiratory infection in bovine is most important cause of morbidity and mortality and also leads to economic losses of farmers in terms of low productivity of affected animals. The infection mostly observed in viral bacterial interaction with other stress factors plays key role in development of sub clinical to clinical disease(s). It is generally accepted that the viruses are the primary path...

The influenza viruses are some of the most important human pathogens, causing substantial seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory tract of can result in flooding of the alveolar compartment, development of acute respiratory distress syndrome and death from respiratory failure. Influenza-mediated damage of the airway, alveolar epithelium and a...

Abstract Active immune suppression can mediate the balance between protective cellular immunity and harmful immunopathology. This occur locally, at an infection site, or in regional draining lymph nodes (dLN). Immune regulation is of particular importance sites such as lung where aberrant immunopathology result loss tissue function. We have recently identified a novel population CD11b+CD103+CCR...

Human metapneumovirus (hMPV) is a recently isolated virus, mostly associated with acute lower respiratory infection in children, of which symptoms are similar to those of respiratory syncytial virus (RSV) infection. The aim of our study was to determine the frequency of hMPV in hospitalized children with acute respiratory tract disease in Korea. Nasal aspirates from hospitalized children with r...

Vague muscular aches and pains are common in viral infections, especially influenza (Lundberg, 1957). Except in coxsackie infection (Thordarson, Sigurdsson, and Grimsson, 1953), however, objective evidence of myositis has seldom been reported (Middleton, Alexander, and Szymanski, 1970; Hoefnagel, 1970; Mejlszenkier et al., 1973). We describe 8 children in whom clinical and biochemical evidence ...

The introduction of newer molecular methods has led to the discovery of new respiratory viruses, such as human metapneumovirus (hMPV) and human bocavirus (hBoV), in respiratory tract specimens. We have studied the occurrence of hMPV and hBoV in the Porto Alegre (PA) metropolitan area, one of the southernmost cities of Brazil, evaluating children with suspected lower respiratory tract infection ...

Influenza virus tissue tropism defines the host cells and tissues that support viral replication and contributes to determining which regions of the respiratory tract are infected in humans. The location of influenza virus infection along the respiratory tract is a key determinant of virus pathogenicity and transmissibility, which are at the basis of influenza burdens in the human population. A...

Respiratory viruses are a major cause of concern for human population worldwide. Respiratory viral infections make it worse for patients suffering with lung diseases, such as, chronic obstructive pulmonary disease (COPD). Viral infections are one of the major inducers of COPD exacerbation. COPD exacerbations are associated with increased inflammation of the lung airways. Infection of upper resp...