نتایج جستجو برای: virucidal activity

تعداد نتایج: 1134630  

Journal: :Applied microbiology 1969
R W Sidwell G J Dixon L Westbrook E A Dulmadge

A quantitative, reproducible method was developed for the evaluation of the virucidal activity of test gases. Using this method, we determined the virucidal effectiveness of a Steri-Vac ethylene oxide gas sterilizer. Wool gabardine material was exposed to high concentrations of herpes simplex, vaccinia, parainfluenza, or polio viruses and was processed through the sterilizer. Two time-temperatu...

Journal: :Probiotics and antimicrobial proteins 2013
Nicolás I Torres Katia Sutyak Noll Shiqi Xu Ji Li Qingrong Huang Patrick J Sinko Mónica B Wachsman Michael L Chikindas

In the present study the antiviral properties of the bacteriocin subtilosin against Herpes simplex virus type 1 (HSV-1) and the safety and efficacy of a subtilosin-based nanofiber formulation were determined. High concentrations of subtilosin, the cyclical antimicrobial peptide produced by Bacillus amyloliquefaciens, were virucidal against HSV-1. Interestingly, at non-virucidal concentrations, ...

Journal: :Journal of virology 2013
Xiuying Liu Yibing Huang Min Cheng Ling Pan Youhui Si Guirong Li Yuqiang Niu Lianjing Zhao Jin Zhao Xiang Li Yuxin Chen Wei Yang

Chronic infection by hepatitis C virus (HCV) is a cause of the global burden of liver diseases. HCV entry into hepatocytes is a complicated and multistep process that represents a promising target for antiviral intervention. The recently reported amphipathic α-helical virucidal peptide (C5A) from the HCV NS5A protein suggests a new category of antiviral drug candidates. In this study, to identi...

Journal: :Metal-Based Drugs 1996
T. Varadinova S. Shishkov M. Panteva P. Bontchev

Cobalt, being essential metal, influences different physiological and enzymatic functions. As cobalt does not accumulate in the body, Co-compounds have relatively low toxicity. The aim of the present study is the effect of complexes of Co(II) with aminoacids - lysine, arginine, histidine and serine on HSV-1 replication. No effect of [O(2)Co(his)(4)].nH(2)O and [O(2)Co(arg)(2)].nH(2)O on HSV-1 i...

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