background during the four steps of the valsalva maneuver (vm), opposite changes can be observed in some physiologic parameters. manifestations of the vm in the electrocardiogram (ecg) have been studied in detail, but there have been few reports comparing vm-related biochemical and hemodynamic changes with a focus on the strain phase of the vm. objectives we studied strain-related ecg changes d...

Dose-dependent pharmacokinetic of phenytoin necessitates the estimation of the maximum rate of metabolism (Vm) and the Michaelis-Menten constant (Km) in a concerned population. The aim of this study was to determine the pharmacokinetic parameters of phenytoin in a sample of Iranian patients to optimize the antiepileptic pharmacotherapy. Fourty patients who received a constant dose of phenytoin ...

Glioblastoma is one of the most common brain tumors in adults with poor prognosis, aggressiveness, and treatment resistance. Vasculogenic mimicry (VM) consists of generating vascular-like channels by tumor cells, independent of endothelial angiogenesis. Studies showed in glioblastoma, the proportion of VM to all vascular channels is associated with poor prognosis and higher invasiveness levels....

Energy efficiency has become an increasingly important concern in data centers because of issues associated with energy consumption, such as capital costs, operating expenses, and environmental impact. While energy loss due to suboptimal use of facilities and non-IT equipment has largely been reduced through the use of best-practice technologies, addressing energy wastage in IT equipment still ...

The fast growing demand for computational power utilized by modern applications with rapidly changing Cloud computing technology have directed to the foundation of large-scale virtualized data centers. Such data centers consume massive amounts of electrical energy resulting in high operating costs and carbon dioxide (CO2) emissions. Dynamic consolidation of virtual machines (VMs) using Dynamic ...

In the last decade, users can access their applications, data, and services via cloud from any location with an internet connection. The scale of heterogeneous environments is continuously growing due to development computing-intensive smart devices. A data center central processing unit environment, it made up hardware-oriented machines known as Physical Machines (PMs) or server software-orien...

The energy used by cloud data centers (CDCs) to support large volumes of storage and computation is dramatically increasing as the scope services continues expand. This puts a greater burden on environment results in higher expenses for providers. Virtualization migration consolidation have been widely current CDCs achieve ser-vice reduce consumption (EC). study divides fundamental tasks virtua...