OBJECTIVE We investigate the mechanisms of diagnostic error in primary care consultations to detect warning signs for possible error. We aim to identify places in the diagnostic reasoning process associated with major risk indicators. DESIGN A qualitative study using semistructured interviews with open-ended questions. SETTING A 2-month study in primary care conducted in Oxfordshire, UK. ...

PURPOSE To promote awareness of primary immunodeficiency (PID), the "10 warning signs" of PID and an immunodeficiency-related (IDR) score were developed. However, their efficiency in identifying PID cases was not sufficiently evaluated in clinical practice. The objective of this study was to test the validity of the 10 warning signs and IDR score in identifying PID among children with recurrent...

BACKGROUND Awareness of detail in ambiguous complaints may help GPs suspect cancer when a malignancy is present. AIM To study the contribution of symptoms and patient characteristics to GPs' suspicions of cancer being present, and to what degree these suspicions were confirmed. DESIGN AND SETTING Prospective cohort study of patients in 283 rural and urban general practices throughout Norway...