Outward currents through Kir2.1 channels regulate the electrical properties of excitable cells. These currents are subject to voltage-dependent attenuation by the binding of polyamines to high- and low-affinity sites, which leads to inward rectification, thereby controlling cell excitability. To examine the effects of positive charges at the low-affinity site in the cytoplasmic pore on inward r...

In this paper, we present a numerical model to simulate wind waves and hydrodynamics in the estuary. We employ the unstructured-grid SUNTANS model for hydrodynamics, and within this model we implement a spectral wave model which solves for transport of wave action density with the finite-volume formulation. Hydrodynamics is coupled to the wave field through the radiation stress. Based on the un...

The Mistaken Point and Trepassey formations (Conception and St. John’s groups, respectively) comprise a terminal Neoproterozoic, deep-marine succession of fine-grained turbidites and volcanogenic deposits that are part of the Avalonian Terrane. Debris-flow beds, slumped units, the low dispersion of turbidity-current paleoflow directions, and the absence of wave-generated structures together ind...

[1] The time evolution of rip currents in the nearshore is studied by numerical experiments. The generation of rip currents is due to waves propagating and breaking over alongshore variable topography. Our main focus is to examine the significance of wave-current interaction as it affects the subsequent development of the currents, in particular when the currents are weak compared to the wave s...

ion channels are responsible for control of cell function in excitable tissues such as heart and brain and also in organs and tissues traditionally thought to be non- excitable including liver and epithelium. in the present research, the effect of lead (pb2+) on ca2+ -dependent action potential and currents was studied in f77 neuronal soma membrane of helix aspersa. for this purpose, action pot...

this study examines votes, ideologies and goals of iran’s cultural-intellectual currents after the islamic revolution in order to describe their scale and type impacts on women rights in iran. in the first section, a theoretical explanation of the relationship between social currents and legal demands based on social realism approach along with viewpoints of scholars who believe in the correlat...

Analyzing the vortex-induced vibration of a slender marine structure withlength to diameter ratio up to 200 is the objective of this study. This slender is free to move in both in-line and cross flow directions and immersed completely in water. Three different types of shear currents pass on it and cause to vibrate slender in different forms. Nowadays, these vibrations are very important for de...

As the first phase of a series of monitoring and modeling studies of Iranian coastal areas, Chabahar Bay, located on the north coast of the Gulf of Oman, was under a comprehensive monitoring and modeling study in 2006-2007. The study included an extensive one-year field measurements program to help understanding the ongoing processes in the bay and provide inputs or boundary conditions and vali...

Sixty-day simulations of the subinertial continental shelf circulation off Oregon are performed for a hindcast study of summer 1999. Model results are compared with in situ currents, high-frequency radar–derived surface currents, and hydrographic measurements obtained from an array of moored instruments and field surveys. The correlations between observed and modeled alongshore currents and tem...