In a previous study, we reported that a gene mutation of repeat in toxin E (RtxE), a transporter of cytotoxic factors, resulted in a significant impairment of epithelial cell cytotoxicity in Vibrio vulnificus, and that the expression of the rtxE gene was induced by the exposure to the host cells. In this study, we evaluated and compared the effects of co-culture supernatants from V. vulnificus-...

Five young adult Rhesus monkeys were included in this study. The weight of the animals ranged from 3.4 to 4.0 kg, with a mean of 3.6 kg. Each animal was restrained and anesthetized with ketamine HC1 at 25 mg/kg IM. An intravenous fluid of 5% dextrose and water with 1/4 normal saline was initiated and profused at a maintenance rate. Each monkey received intranasal midazolam (VersedTM, Roche Phar...

a Minimal risk is defined as risk that is not greater than the risks “ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests” (46.102 i/50.3 k). b Permission of one parent is sufficient for categories 404/50.51 and 405/50.52; permission of both parents, if reasonably available, is required for 406/50.53 and 407/50.54; the requir...

Dominic Lieven, Abschied von Macht und Würden. Der europäische Adel 1815-1914, Frankfurt (S.Fischer) 1995, 407 S.