نتایج جستجو برای: whole cell patch clamp recoding
تعداد نتایج: 1951713 فیلتر نتایج به سال:
bstract—In the mammalian neocortex, the corpus callos erves as the major source of interhemispheric commun ion, composed of axons from callosal neurons located upragranular (II/III) and infragranular (V/VI) layers. ought to characterize the physiology and morphology upragranular and infragranular callosal neurons in mice ng retrograde tracers and whole-cell patch clamp reco ngs. Whole-cell patc...
We report on a simple and high-yield manufacturing process for silicon planar patch-clamp chips, which allow low capacitance and series resistance from individually identified cultured neurons. Apertures are etched in a high-quality silicon nitride film on a silicon wafer; wells are opened on the backside of the wafer by wet etching and passivated by a thick deposited silicon dioxide film to re...
Upon ejaculation, mammalian spermatozoa have to undergo a sequence of physiological transformations within the female reproductive tract that will allow them to reach and fertilize the egg. These include initiation of motility, hyperactivation of motility and perhaps chemotaxis toward the egg, and culminate in the acrosome reaction that permits sperm to penetrate the protective vestments of the...
The membrane-destabilization properties of the recently-introduced endosomolytic CM18-Tat11 hybrid peptide (KWKLFKKIGAVLKVLTTG-YGRKKRRQRRR, residues 1-7 of cecropin-A, 2-12 of melittin, and 47-57 of HIV-1 Tat protein) are investigated in CHO-K1 cells by using the whole-cell configuration of the patch-clamp technique. CM18-Tat11, CM18, and Tat11 peptides are administered to the cell membrane wit...
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