It is now a year since Sheridan Del?pine brought the serum test for enteric fever prominently before the profession in this country. Since the publication of his admirable paper in the Lancet a large amount of evidence has accumulated in favour of the accuracy of this new method of making a diagnosis, which has always been admitted to be of considerable difficulty. It is not my intention in thi...

Serum samples from 22 patients with proven typhoid fever, 60 febrile nontyphoidal patients, and 120 healthy subjects were tested for immunoglobulin A (IgA), IgG, and IgM anti-Salmonella typhi lipopolysaccharide antibodies by an enzyme-linked immunosorbent assay. The levels of all three classes of immunoglobulin anti-lipopolysaccharide were higher in typhoid patients than in controls; the test f...

It is a commonplace of clinical teaching that tuberculous pleural effusions contain a high proportion of lymphocytes. This was one of two characteristics noticed by Widal (Widal and Ravaut, 1900), the other being an absence or scarcity of mesothelial (" endothelial ") cells. This second feature is more constant than the first, but for some reason has escaped being generally known. Looking back ...

Typhoid fever poses a serious public health problem in Nigeria and is largely diagnosed based on the Widal agglutination test which has been proven to be neither sensitive nor specific. This study determined prevalence of typhoid using both blood culture automated microbiology systems (BD BACTEC). The was carried out among 90 patients attending Murtala Muhammad Specialist Hospital Kano. Out cas...