The alcoholic extract of roots of Dichrostachys cinerea Wight & Arn. (200 and 400 mg/kg, p.o.) was studied for its protective effect against cisplatin-induced renal injury in rats. Cisplatin (6mg/kg, i.p.) significantly elevated serum markers level, increased urinary protein excretion, reduced urine to serum creatinine ratio and creatinine clearance. In curative regimen, the alcoholic extract e...

Decalepis hamiltonii. Wight and Arn. (Asclepiadaceae) has been extensively used in traditional systems of medicine for a wide range of ailments. Phytochemical studies have shown the presence of many valuable compounds such as saponins, tannins, flavonoids, phenolics, triterpenes, ketones, aldelydes, resinol, sterols, inositol, fatty acids, volatile flavour compounds, cardiac glycosides, volatil...

Calcaneus osteomyelitis is a rare infection in newborns. Invasive procedures, prematurity and low birth wight are some causative factors. The clinical signs may be mild. We report a neonate with calcaneous osteomyelitis which was secondary to a Guthrie test sample. She was admitted to hospital with swelling, redness and increased temperature on her heel. Superficial tissue ultrasound showed flu...

Stephen Evanko: Stephen Evanko received his M.S. and Ph.D. degrees from the University of New Mexico in 1990 and 1993, respectively. His work focused on the response of connective tissues to alterations in mechanical loading and the role of proteoglycans and hyaluronan in the material properties of tendon and fibrocartilage. He then joined the laboratory of Dr. Thomas Wight in the Department of...

The effect of a chloroform soluble fraction (F-A) of the acetone extract of twigs of Sarcostemma brevistigma Wight on contractions induced by oxytocin and KCl, in the isolated rat uterine smooth muscles, has been evaluated. At concentrations of 32.8 μg/ml, the F-A significantly inhibited (P<0.001) the contractions induced by 60 mM KCl in Ca, containing physiological salt solution to the extent ...

We wish to thank R.J. Kurukulaaratchy and co-workers for their positive response to our article [1]. We were happy to see that our paper encouraged the Isle of Wight Birth Cohort (IOWBC) to assess the prognosis of early recurrent wheeze into the beginning adulthood. As the corresponding findings in the IOWBC, with its high 18-year follow-up rate of 90% [2], are in line with those from our Envir...