During the search for novel natural products from entomopathogenic Xenorhabdus doucetiae DSM17909 and X. mauleonii DSM17908 novel peptides named xenoamicins were identified in addition to the already known antibiotics xenocoumacin and xenorhabdin. Xenoamicins are acylated tridecadepsipeptides consisting of mainly hydrophobic amino acids. The main derivative xenoamicin A (1) was isolated from X....

Xenorhabdus nematophila is an insect pathogen and produces protein toxins which kill the larval host. Previously, we characterized an orally toxic, large, outer membrane-associated protein complex from the culture medium of X. nematophila. Here, we describe the cloning, expression, and characterization of a 17-kDa pilin subunit of X. nematophila isolated from that protein complex. The gene was ...

This study was carried out to determine the antifungal effects of supernatant produced by bacterium Xenorhabdus szentirmaii, which is associated with soil-inhabiting entomopathogenic nematodes, on important plant pathogenic fungi, Fusarium verticilliodes, oxysporum f.sp lycopersici, radicis Botrytis cinerea, Sclerotinia sclerotiorum and Phytophthora nicotianae. The 1, 3, 5 7% concentrations X. ...

From the characterisation, partial 16 S gene sequences obtained for two bacteria were subjected to blast-bootstrap analysis obtain phylogenetic tree. In assessing similarity of Xenorhabdus bovienii with five other spp., it was found be 96% similar X. nematophila and japonica Accession Numbers D78006 NR027194 respectively. The closer beddingii 95% kazodoii 97% poinarii. tree, species belong gene...

Photorhabdus and Xenorhabdus are the bacterial symbionts of insect pathogenic nematodes, Heterorhabditis Steinernema, respectively. This study aims to characterize from Mizoram, North-east India evaluate their antibacterial potential. The isolates were characterized using recA gyrB gene regions. ethyl acetate extract was tested against strains, viz. Escherichia coli (ATCC 10536), Klebsiella pne...

Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin. In the present study, a novel homolog of RelE toxin designated as Xn-relE toxin from Xenorhabdus nematophila possessing its own antitoxin des...

Bacterial histidine kinase/response regulator systems operate at the interface between environmental cues and physiological states. Escherichia coli contains two LytS/LytTR-type histidine kinase/response regulator systems, BtsS/BtsR (formerly YehU/YehT) and YpdA/YpdB, which have been identified as pyruvate-responsive two-component systems. Since they exhibit remarkable similarity, we analyzed t...