The effect of different metal ions on the intestinal transport and the antibacterial activity of cefadroxil [(6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid] was investigated. The [14C]Gly-Sar uptake via PEPT1 was inhibited by Zn2+ and Cu2+ treatment in a concentration-dependent manner (Ki values 107 ± 23 and 19 ± 5 ...

Zinc, an essential trace element, is present in unusually high concentrations in the chorioretinal complex relative to most other tissues. Because little has been known about the interactions between the retinal pigment epithelium and free or protein-associated zinc, we studied 65Zn uptake by human retinal pigment epithelium in vitro. When monolayers were exposed to differing concentrations fro...

BACKGROUND Many studies demonstrate that the elderly consume a nutritionally inadequate diet that includes deficiencies in macro- and microelements; iron and zinc being significant examples of the former. OBJECTIVES To assess the adequacy of dietary iron and zinc intakes in the elderly. MATERIAL AND METHODS The study was conducted on n = 102 elderly persons, participating in the PolSenior P...

Odstránenie Cd, Zn, Pb a Cu sorpciou na vylúhovanom zvyšku z produkcie Ni A leaching resudue from the nickel production (LRNi), was used to study the removal of selected bivalent cations (Cd, Pb, Cu and Zn) from model aqueous solutions. Batch-type experiments have been performed in solutions with initial concentrations of heavy metals in the range of 20-400 mg.L and the adsorbent dosage 2 g.L. ...

Modern agriculture pays attention to improving agricultural production by producing zinc-enriched crops through zinc-solubilizing bacteria strengthen the bioeconomy. Zinc deficiency in soil reduces plant growth and also leads less uptake of zinc edible portion plants. Therefore, content parts plants can be increased biofortification approach. However, most approaches are laborious need expensiv...