ofthe various factors that go into the computation better; it also segregates the least reliable and error-prone model-dependent components into terms that can be identified and minimized. Regional cerebral glucose utilization is calcu lated as: IT C@†• (T) †" K'I' I C@(t) e@ +k@)(Tt) dt JO (IfTC(t) fTC@(t) e@ +k@)(Tt) dt)-@-dt-i; 0 @ 0 Eq.! where C@' represents total concentration of ‘4C...

Highly DNA-reactive <*,/3-unsaturated aldehydes such as acrolein and crotonaldehyde are common environmental pollutants present in cigarette smoke and automobile exhaust and are also released endogenously by lipid peroxidation. Acroleinand crotonaldehyde-derived l,.V--prop;modeoxyguanosine (AdG and CdG, respectively) have been detected in the tissues of carcinogen-treated rodents and as backgro...

C —¿ > T transitions at CpG sites are the most prevalent mutations found in the p53 tumor suppressor gene in human colon tumors and in the germline (Li-Fraumeni syndrome). All of the mutational hot spots are methylated to 5-methylcytosine, and it has been hypothesized that the majority of these mutations are caused by spontaneous hydrolytic deamination of this base to thymine. We have previou...

In an attempt to better understand breast tumors sensitivity or resis tance to anticancer drugs, the main drug-metabolizing enzyme systems were evaluated in both breast tumors and their corresponding peritumoral tissues in 12 patients. The following enzymes were assayed by Western blot: cytochromes P-4SO (1A1/A2, 2B1/B2, 2C8-10, 2E1, 3A4); glutathione .S'-transferases (GST-a, -u, and -TI); and ...

Let A be an abelian variety,  be the dual abelian variety. The Fourier-Mukai transform is an equivalence between the derived categories of coherent sheaves Db(A) and Db(Â). Notice that there is a ”symplectic” line bundle LA on (Â×A)2, namely, LA = p14P⊗√∈∋P where P is the Poincaré line bundle on Â×A, such that the standard embeddings A ⊂ Â×A and  ⊂ Â×A are ”lagrangian” with respect to LA, i.e...

In the Bargmann representation of quantum mechanics, physical states are mapped into entire functions of a complex variable z, whereas the creation and annihilation operators â and â play the role of multiplication and differentiation with respect to z, respectively. In this paper we propose an alternative representation of quantum states, conjugate to the Bargmann representation, where the rol...

homoalcophosphamide by the procedure of Corey and Kim (7) gave diethylaldophosphamide and diethylhomoaldophos phamide, respectively (Chart 2). Diethylaldophosphamide was characterized by mass spectral analysis [m/e 283, 1 Cl, M2— CH2C1@; m/e 192, no Cl, M —N(CH2CH2C1)2] and by positive qualitative tests as an aldehyde and an alkylating agent. Complete purification of diethylaldophosphamide ...

â â â  â  â â â â â â â  abstract â  the abtalkh formation in the kopeh-dagh basin in northeastern iran with an age of late cretaceous (turonian – santonian) is selected to evaluate resolution of magnetic susceptibility for assessing sea level fluctuations. thirty-nine shale samples were collected and studied for magnetic susceptibility and palynology. assuming the average ms magnitude as the...

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since Φ̂(ω)Φ̂(−θ) = e−σ2(‖ω‖2+‖θ‖2)/4 = Φ̂(ω−θ)e−σ2(ω·θ∗+ω∗·θ)/4. (9) Assuming X is near equilibrium then, at reasonably low temperature, the power spectrum of the point configuration shows the bluenoise properties, i.e., has a delta at the origin and vanishes in an annulus around it. The approximation function Â(ω) equals to this function times Φ̂(ω) which is zero outside the angulus and hence Â(ω...