نتایج جستجو برای: α lipoic acid
تعداد نتایج: 893681 فیلتر نتایج به سال:
The present experiment was carried out to investigate the effectivness of -lipoic acid in allevating the toxicity of aluminium phosphide on biochemical parameters, free radicals and enzyme activities in plasma, liver and kidney of male rats. Animals were orally treated with aluminium phosphide, -lipoic acid and their combination for 30 consecutive days. Treatment with aluminium phosphide led to...
Cofactor disorders of mitochondrial energy metabolism are a heterogeneous group of diseases with a wide variety of clinical symptoms, particular metabolic profiles and variable enzymatic defects. Mutations in NFU1, BOLA3, LIAS and IBA57 have been identified in patients with deficient lipoic acid-dependent enzymatic activities and defects in the assembly and activity of the mitochondrial respira...
The objective of this study was to determine the effects of alpha lipoic acid on the performance and serum lipid profile in broiler chicken. In this study, eighty, day-old Venn Cobb commercial broiler chicks broiler chicks were randomly distributed into two treatment groups with four replicates of ten birds each and the birds were fed with experimental diets T1 (Control ration as per BIS [1992]...
Th is study was designed to investigate whether inclusions of coenzyme Q10, alpha lipoic acid and their combination into diets of hens improve egg quality characteristics. Forty-eight, 33 weeks old Lohmann Brown hens were assigned randomly to four groups of 12 hens each and fed either a basal diet or basal diet supplemented with 2 g/ kg coenzyme Q10, 0.4 g/kg alpha lipoic acid and 2 g/kg coenzy...
Unlike normal cells, tumor cells survive in a specific redox environment where the elevated reactive oxygen species contribute to enhance cell proliferation and to suppress apoptosis. Alpha-lipoic acid, a naturally occurring reactive oxygen species scavenger, has been shown to possess anticancer activity, due to its ability to suppress proliferation and to induce apoptosis in different cancer c...
Considerable evidence indicates that hyperglycemia increases oxidative stress and contributes to the increased incidence of atherosclerosis and cardiovascular complications in diabetic patients. To examine the effect of alpha-lipoic acid, a potent natural antioxidant, on atherosclerosis in diabetic mice, 3-month-old apolipoprotein (apo) E-deficient (apoE(-/-)) mice were made diabetic by adminis...
OBJECTIVES Evaluation of therapeutic potentials of α-lipoic acid (α-LA), L-carnitine, Nigella sativa (N. sativa) or combination of them in carbohydrate and lipid metabolism of DM type I. METHODS Rat model of diabetes was induced by single i.p injection of Streptozocin (STZ) 65 mg/kg. The rats were randomly assigned to 6 groups (G): healthy reference (HR), diabetic (DM), DM treated with α-lipo...
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