Emery-Dreifuss muscular dystrophy (EMD) is characterised by (1) early contractures of the Achilles tendons, elbows, and postcervical muscles, (2) slowly progressive muscle wasting and weakness with a predominantly humeroperoneal distribution in the early stages, and (3) cardiomyopathy with conduction defects and risk of sudden death. Inheritance is usually X linked recessive but can be autosoma...

The purpose of this study was to compare the clinical and radiographic success rates of two different pulpotomy agents: one novel agent, the biologically active odontogenic protein enamel matrix derivative (EMD) versus formocresol (FC). A randomized, single-blind, split-mouth study was used with a sample of 15 children aged 4 to 7 years (mean age, 5 +/- 0.73 years). A total of 15 pairs of teeth...

We reviewed the literature on the efficacy of enamel matrix derivative (EMD) in comparison with open flap debridement, guided tissue regeneration (GTR), and bone grafting for the treatment of intrabony defects. We searched four major electronic databases for randomized controlled trials (RCTs) with at least one year of follow-up. Several journals were handsearched with no language restrictions....

The empirical mode decomposition (EMD) is a powerful tool for non-stationary signal analysis. It has been used successfully for sound and vibration signals separation and time-frequency representation. Linear time-frequency analysis (TFA) is another powerful tool for non-stationary signal. Linear TFAs, e.g. short-time Fourier transform (STFT) and wavelet transform (WT), depend linearly upon the...

BACKGROUND Treatment of large bone defects due to trauma, tumor resection, or congenital abnormalities is challenging. Bone tissue engineering using mesenchymal stem cells (MSCs) represents a promising treatment option. However, the quantity and quality of engineered bone tissue are not sufficient to fill large bone defects. The aim of this study was to determine if the addition of enamel matri...

The study examined the response of MG63 to Enamel Matrix Derivative (EMD) on the coarse-grit-blasted and acid-etched surface disks. We characterized associated changes in proliferation and differentiation related intracelluar signaling molecular including mitogen activitied protein kibase. The major groups of MAPKs (ERK1/2, cJUN-terminal kinases, JNK and p38-MAPK) have been characterized in pre...

Enamel matrix derivative (EMD) can mimic odontogenic effects by inducing the proliferation and differentiation of connective tissue progenitor cells, stimulating bone growth and arresting epithelial cells migration. To the best of our knowledge, there is no data indicating that any active component of EMD reduces epithelial cell viability. The present study examines the impact of commercial lyo...