PURPOSE Botanical preparations are widely used by patients with prostate cancer. Scutellaria baicalensis, a botanical with a long history of medicinal use in China, was a constituent of the herbal mixture PC-SPES, a product that inhibited prostate cancer growth in both laboratory and clinical studies. Due to the difficulties encountered when evaluating the efficacy of complex natural products, ...

The number of fully active antibiotic options that treat nosocomial infections due to multidrug-resistant Acinetobacter baumannii (A. baumannii) is extremely limited. Magnolia officinalis, Mahonia bealei, Rabdosia rubescens, Rosa rugosa, Rubus chingii, Scutellaria baicalensis, and Terminalia chebula plant extracts were previously shown to have growth inhibitory activity against a multidrug-resi...

Spatial climate heterogeneity may not only affect adaptive gene frequencies but could also indirectly shape the genetic structure of neutral loci by impacting demographic dynamics. In this study, the effect of local climate on population genetic variation was tested in two phylogenetically close Scutellaria species in Taiwan. Scutellaria taipeiensis, which was originally assumed to be an endemi...

A cDNA encoding chalcone synthase (CHS), the key enzyme in flavonoid biosynthesis, was isolated from hairy root cultures of Scutellaria viscidula Bunge by rapid amplification of cDNA ends (RACE). The full-length cDNA of S. viscidula CHS, designated as Svchs (GenBank accession no. EU386767), was 1649 bp with a 1170 bp open reading frame (ORF) that corresponded to a deduced protein of 390 amino a...

Two rust fungi from Iran are described as new species, viz. Puccinia hedjaroudei on Scutellaria multicaulis (Lamiaceae) and Phragmidium gorganense on Rubus caesius (Rosaceae). A key to the species of Phragmidium on Rubus spp. in Iran is also provided. All holotypes are preserved in the fungus reference collection of the Ministry of Jihad-e Agriculture (IRAN), located in Department of Botany of ...

Aggregation of alpha-synuclein (α-SN) is a key pathogenic event in Parkinson's disease (PD) leading to dopaminergic degeneration. The identification of natural compounds inhibiting α-SN aggregation may have a major role in treating PD. Different Scutellaria species are known as valuable medicinal plants, primarily due to their high flavonoid levels. Scutellaria pinnatifida (S. pinnatifida) is e...

Wogonin and baicalein are bioactive flavones in the popular Chinese herbal remedy Huang-Qin (Scutellaria baicalensis Georgi). These specialized flavones lack a 4'-hydroxyl group on the B ring (4'-deoxyflavones) and induce apoptosis in a wide spectrum of human tumor cells in vitro and inhibit tumor growth in vivo in different mouse tumor models. Root-specific flavones (RSFs) from Scutellaria hav...

تعتبر الدراسات السكانية ذات أهمية كبيرة في إبراز جوانب مهمة حول السكان من حيث حجم التغييرات التي تحصل أعدادهم فترات متتالية والتطور الذي يحصل بتركيبهم النوعي نسب أفراد كل جنس والتباين الموجود بنسب النوع فئاتهم العمرية المختلفة وكذلك التطور التركيب العمري ونسبة فئة عمرية لمعرفة نتائج حولهم كنسبة الإعالة والعمر الوسيط والكثير المؤشرات الأخرى المتعلقة بها. تهدف الدراسة الى تسليط الضوء على والتغيير...

یکی از دلایل اصلی بروز خطا در ساخت بند موصولی سوی زبان آموزان فارسی که مشغول یادگیری آلمانی هستند، استفاده ضمیر برای عنوان می شود با هسته به لحاظ جنس دستوری و شمار مطابقه دارد. مقابل، تنها حرف ربط «که» بهره برد ارتباط نحوی یا معنایی ندارد. دیگر، راهبردهایی هر دو مورد قرار گیرند نیز کاملا متفاوت اند. بر اساس فرضیه پژوهش حاضر، نظر رسد بیشترین خطاها بخش رخ دهند: یک سو، انتخاب نادرست روبرو هستیم. ع...