IL-6 signaling via the soluble IL-6 receptor (sIL-6r) has been shown to increase primary afferent responsiveness to noxious stimuli. This finding prompted us to test the hypothesis that IL-6 and sIL-6r would increase the exercise pressor reflex in decerebrate rats with freely perfused femoral arteries. We also tested the hypothesis that soluble glycoprotein (sgp)130, an inhibitor of IL-6/sIL-6r...

The solid immersion lens (SIL), invented by Mansfield and Kino in 1990 [1], attracts potential application in the field of imaging solid state devices, where the structures are buried deep into the substrate such as in integrated circuits. This is due to the ability of SIL to provide sub-surface imaging with better resolution than a conventional microscopy system. Many papers have dealt with th...

SIL (SPRITE Input Language) is developed as an intermediate format between a variety of specification languages and a number of input formats of synthesis tools and silicon compilers. The second aim in its development was to get a useful language backbone for transformational design, Therefore, SIL is based on a formal semantical model and on only a small number of basic concepts. Transformatio...

Stable isotope labeling (SIL) still has not been used very much in pediatric and perinatal clinical pharmacology. However, this method has numerous advantages. It allows one to determine the concentration of drugs with great sensitivity, thereby allowing quantification in small amounts of biologic samples. It also allows quantification with great specificity, eliminating interference by drug me...

Sil®er is known to strongly affect the adsorpti®e properties of zeolites. In the synthesis ( ) of mixed Li,Ag low-silica X-type LSX zeolite, adding ®ery small amounts of sil®er and specific dehydration conditions results in a sorbent with enhanced adsorpti®e characteristics for air separation. The location of the extraframework sil®er in relation to the aluminosilicate framework is of primary i...

BACKGROUND Aim of this study was to elucidate the relation between localised inflammatory heart disease and endothelial dysfunction in the peripheral circulation, considering circulating cytokines as a potential link. METHODS In 38 patients with non-ischemic heart disease, myocardial biopsies were examined for myocardial inflammation (immunohistology) and virus persistence (PCR). Cytokines (s...

We conducted a case-control study of the association between SIL and HPV among whites (W) , African Americans (AA), and Hispanics (H) in Harris County, Tex a s . Cases were identified at M.D. Anderson Cancer Center Colposcopy Clinic. C o n t rols were identified among women obtaining routine Pap screening at two Harris County Health De p a rtment Clinics. H P V was detected by a PCR-based fluor...

BACKGROUND Silymarin (SIL) is an active extraction of the silybum marianum, milk thistle, which is an ancient medicinal plant for treatment of various liver diseases for centuries. This study is to assess the therapeutic effect of SIL in the treatment of nonalcoholic fatty liver disease through meta-analysis. METHODS Published randomized controlled trials (RCTs) were included from electronic ...

Adhesion molecules such as VCAM-1 and ICAM-1 are increased in the central nervous system (CNS) during inflammatory responses and contribute to extravasation of leukocytes across the blood-brain barrier (BBB) and into CNS parenchyma. Astrocytes contribute to the structural integrity of the BBB and can be induced to express VCAM-1 and ICAM-1 in response to cytokines such as TNF-alpha, IL-1beta, a...

We monitored the effectiveness of lymphoma therapy by measuring the serum levels of soluble CD44std (sCD44std) and soluble CD44v6 (sCD44v6). Furthermore, we measured the level of soluble interleukin 2 receptor (sIL-2R). A total of 24 patients with non-Hodgkin's lymphoma were enrolled. sCD44std, sCD44v6, and sIL-2R on serum were measured using ELISA system. In all patients, only the sIL-2R level...