This prospective study compared diagnostic and prognostic value of conventional cytologic (CC) examination and flow cytometry (FCM) of baseline samples of cerebrospinal fluid (CSF) in 174 patients with newly diagnosed aggressive non-Hodgkin lymphoma (NHL). FCM detected a neoplastic population in the CSF of 18 of 174 patients (10%), CC only in 7 (4%; P < .001); 11 patients (14%) were discordant ...

dendritic cells (dcs) induce pathogen-specific t cell responses. we comprehensively studied the effects of addition of maturation stimulus, fibroblasts (fibroblast conditioned medium), pha activated t cells (t cell conditioned medium), and mixture of fibroblast &amp; pha activated t cells (fcm-tccm) conditioned media on maturation of dcs. monocytes were cultured with gm-csf and il-4 for five da...

Fiber-optics confocal microscopy (FCM) is an emerging imaging technology with various applications in basic research and clinical diagnosis. FCM allows for real-time in situ microscopy of tissue at sub-cellular scale. Recently FCM has been investigated for cardiac imaging, in particular, for discrimination of cardiac tissue during pediatric open-heart surgery. FCM relies on fluorescent dyes. Th...

One of the strategies a company uses to retain its customers is Customer Relationship Management (CRM). CRM manages interactions and supports business build mutually beneficial relationships between companies customers. The utilization information technology, such as data mining used manage data, critical in order be able find out patterns made by when processing transactions. Clustering techni...

Keywords: Cluster analysis Fuzzy clustering Fuzzy c-means (FCM) Initialization Bias correction Probability weight a b s t r a c t Fuzzy clustering is generally an extension of hard clustering and it is based on fuzzy membership partitions. In fuzzy clustering, the fuzzy c-means (FCM) algorithm is the most commonly used clustering method. Numerous studies have presented various generalizations o...

Erythropoiesis may be limited by absolute or functional iron deficiency or when chronic inflammatory conditions lead to iron sequestration. Intravenous iron may be indicated when oral iron cannot address the deficiency. Ferric carboxymaltose (FCM) is a nondextran iron preparation recently approved in the United States for intravenous treatment of iron deficiency anemia (IDA) in adult patients w...

There is limited safety information about ferric carboxymaltose (FCM), a new intravenous iron preparation. This randomized, crossover study compared the safety and tolerability of double-blinded intravenous doses of FCM or placebo in patients with iron deficiency anemia. Subjects (559) with iron deficiency anemia received a dose of either FCM (15 mg/kg, maximum 1000 mg) over 15 minutes or place...

OBJECTIVE An excess of metalloproteinases (MMPs) over tissue inhibitors of metalloproteinases (TIMPs) may favor atherosclerotic plaque rupture. We compared TIMP levels in nonfoamy and foam-cell macrophages (FCM) generated in vivo. METHODS AND RESULTS In vivo generated rabbit FCM exhibited 84% reduced TIMP-3 protein compared to nonfoamy macrophages, and immunocytochemistry revealed a TIMP-3 ne...

OBJECTIVE To improve the quality of expectation maximizing (EM) for brain image segmentation, and to evaluate the accuracy of segmentation results. METHODS This brain segmentation study was conducted in Universiti Putra Malaysia in Serdong, Malaysia between February and November 2010 on simulated and real images using novel improvement for EM. The EM-1 (proposed algorithm) was compared with n...