Background The antitumoral efficacy of aqueous Viscum album extracts is attributed to the presence lectins and viscotoxins. However, previous studies demonstrated an activity European V. ethanolic homeopathic tinctures (VAHT) prepared according methodology. Aims To investigate seasonal influences (summer winter) in metabolomic profile ssp. mother evaluate some VAHT 3D tumor spheroid models. Met...

Extracts of mistletoe (Viscum album) are intensively used in complementary medicine, but their mechanisms are not fully understood in most cases, and the effects on metabolism have not been investigated in detail. However, some biologically active natural products are well known to provoke unexpected cellular responses. They reduce overexpression of heat shock proteins (Hsps) in cancer ce...

Tumor cells have the capacity to secrete immunosuppressive substances in order to diminish dendritic cell (DC) activity and thereby escape from immune responses. The impact of mistletoe (Viscum album) extracts (VAE), which are frequently used as an additive anti-cancer therapy to stimulate the immune response, is still unknown. Using a human cellular system, the impact of two different VAE (VAE...