Hemoblobin A1c is the most important parameter for the monitoring of metabolic control of patients with diabetes mellitus. The purpose of this study was to adapt the Mono S method to a conventional HPLC system, allowing highly selective HbA1c determination without the acquisition of kits or the use of dedicated systems The results obtained were compared to the Tinaquant® immune turbidimetric me...

In this review article determines the different analytical methods for quantitative establishment of Erlotinib by using HPLC, HPLCMS, HPLC-UV, LC-MS/MS. Pharmaceutical method development requires valid procedures and qualitative analysis in Pharmaceuticals dosage formulations human serum. This assessment explains that superiority HPLC/LC-MS reviewed is based on drugs formulations, (API), biolog...

Background Mycophenolic acid (MPA) concentration measured by homogeneous particle-enhanced turbidimetric inhibition immunoassay (PETINA) may be overestimated due to its cross-reactivity with pharmacologically inactive MPA glucuronide (MPAG), as well as other minor metabolites, accumulated with renal function impairment or co-administered cyclosporine A. In contrast, high-performance liquid chro...

a simple, rapid and sensitive high-performance liquid chromatographic (hplc) method for the determination of risperidone in human plasma was developed. an hplc system based on a nucleosil c8 column (150?4 mm) and a uv detector (?= 280 nm) were used. a mixture of sodium dihydrogen phosphate buffer-acetonitrile (55:45, v/v) adjusted to ph 6.0 at a flow rate of 1.5 ml min-1 was used as mobile phas...

background and objective: the opportunistic pathogen pseudomonas aeruginosa secrets a capsule-like polysaccharide called alginate which is important for evasion of host defenses, especially in patients with suppressed immunity. method of alginate determination has an important role in the study of microbial alginate. in this study, a novel method for alginate determination by highperformance li...

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